F-Met I

Details

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Internal ID 7d306073-f857-4778-a257-a19571c85e42
Taxonomy Nucleosides, nucleotides, and analogues > Purine nucleosides
IUPAC Name (2S,3R,4S,5S,6R)-2-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-2-fluoro-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
SMILES (Canonical) C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)(CO)F)OC4C(C(C(C(O4)CO)O)O)O)O)N
SMILES (Isomeric) C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@](O3)(CO)F)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)N
InChI InChI=1S/C16H22FN5O9/c17-16(2-24)11(30-15-9(27)8(26)7(25)5(1-23)29-15)10(28)14(31-16)22-4-21-6-12(18)19-3-20-13(6)22/h3-5,7-11,14-15,23-28H,1-2H2,(H2,18,19,20)/t5-,7-,8+,9-,10-,11+,14-,15+,16-/m1/s1
InChI Key VDJLQFBBLCGKQS-ZGQJCEQDSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C16H22FN5O9
Molecular Weight 447.37 g/mol
Exact Mass 447.14015546 g/mol
Topological Polar Surface Area (TPSA) 219.00 Ų
XlogP -2.90

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of F-Met I

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.36% 96.09%
CHEMBL3589 P55263 Adenosine kinase 95.70% 98.05%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.71% 91.11%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 92.59% 94.00%
CHEMBL3137261 O14744 PRMT5/MEP50 complex 91.71% 100.00%
CHEMBL1075162 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor 91.20% 80.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 91.05% 95.89%
CHEMBL221 P23219 Cyclooxygenase-1 89.72% 90.17%
CHEMBL2243 O00519 Anandamide amidohydrolase 89.11% 97.53%
CHEMBL2345 P51812 Ribosomal protein S6 kinase alpha 3 88.77% 95.64%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.60% 86.33%
CHEMBL5524 Q99873 Protein-arginine N-methyltransferase 1 88.04% 96.67%
CHEMBL3714130 P46095 G-protein coupled receptor 6 88.02% 97.36%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.93% 97.09%
CHEMBL4523377 Q86WV6 Stimulator of interferon genes protein 87.26% 95.48%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.97% 94.45%
CHEMBL3286 P00749 Urokinase-type plasminogen activator 85.42% 97.88%
CHEMBL5339 Q5NUL3 G-protein coupled receptor 120 84.40% 95.78%
CHEMBL3891 P07384 Calpain 1 83.90% 93.04%
CHEMBL3401 O75469 Pregnane X receptor 83.79% 94.73%
CHEMBL218 P21554 Cannabinoid CB1 receptor 83.24% 96.61%
CHEMBL5678 P34947 G protein-coupled receptor kinase 5 81.73% 88.00%
CHEMBL4101 P17612 cAMP-dependent protein kinase alpha-catalytic subunit 81.08% 82.86%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 80.83% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146682819
LOTUS LTS0075821
wikiData Q105284204