Esulatin M

Details

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Internal ID de412a95-d7c8-4556-bd48-88961d48aff6
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Jatrophane and cyclojatrophane diterpenoids
IUPAC Name [(1S,2S,3aR,5R,6E,9R,11R,13R,13aR)-1,3a,13-triacetyloxy-2,5,8,8-tetramethyl-12-methylidene-11-(2-methylpropoxy)-4-oxo-2,3,5,9,10,11,13,13a-octahydro-1H-cyclopenta[12]annulen-9-yl] pyridine-3-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C36H49NO10/c1-20(2)19-43-28-16-29(46-34(42)27-12-11-15-37-18-27)35(9,10)14-13-21(3)33(41)36(47-26(8)40)17-22(4)31(44-24(6)38)30(36)32(23(28)5)45-25(7)39/h11-15,18,20-22,28-32H,5,16-17,19H2,1-4,6-10H3/b14-13+/t21-,22+,28-,29-,30-,31+,32+,36-/m1/s1
InChI Key NRLHNKOYUVCFAL-SLNBGHRSSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C36H49NO10
Molecular Weight 655.80 g/mol
Exact Mass 655.33564676 g/mol
Topological Polar Surface Area (TPSA) 144.00 Ų
XlogP 5.30

Synonyms

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CHEMBL1812478

2D Structure

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2D Structure of Esulatin M

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.87% 96.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 96.71% 86.33%
CHEMBL2581 P07339 Cathepsin D 96.70% 98.95%
CHEMBL1951 P21397 Monoamine oxidase A 96.31% 91.49%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 96.19% 89.34%
CHEMBL2996 Q05655 Protein kinase C delta 94.73% 97.79%
CHEMBL253 P34972 Cannabinoid CB2 receptor 93.98% 97.25%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.55% 85.14%
CHEMBL221 P23219 Cyclooxygenase-1 91.45% 90.17%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.10% 99.23%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 86.05% 94.80%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 85.75% 94.00%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 85.58% 91.11%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.97% 89.00%
CHEMBL202 P00374 Dihydrofolate reductase 84.66% 89.92%
CHEMBL4208 P20618 Proteasome component C5 84.24% 90.00%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 84.22% 98.75%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.95% 95.89%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.78% 94.45%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.01% 97.09%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 82.62% 91.07%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.26% 100.00%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 81.24% 95.71%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 80.94% 82.69%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Euphorbia esula

Cross-Links

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PubChem 56673097
LOTUS LTS0073481
wikiData Q105184647