Epoxycycloartane-1

Details

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Internal ID e53ad208-148f-4ab2-9f02-e6dcd274ab80
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Cycloartanols and derivatives
IUPAC Name (1S,3R,8R,11S,12S,15R,16R)-15-[(2R)-4-[(2R)-3,3-dimethyloxiran-2-yl]butan-2-yl]-7,7,12,16-tetramethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecan-6-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H48O2/c1-19(8-11-24-26(4,5)32-24)20-12-14-28(7)22-10-9-21-25(2,3)23(31)13-15-29(21)18-30(22,29)17-16-27(20,28)6/h19-22,24H,8-18H2,1-7H3/t19-,20-,21+,22+,24-,27-,28+,29-,30+/m1/s1
InChI Key HVNFHQIJHBQZCB-FDIVVELCSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C30H48O2
Molecular Weight 440.70 g/mol
Exact Mass 440.365430770 g/mol
Topological Polar Surface Area (TPSA) 29.60 Ų
XlogP 8.00

Synonyms

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(24R)-24,25-Epoxycycloartan-3-one
CHEMBL462458
DTXSID201246289
184176-69-0
9,19-Cyclolanostan-3-one, 24,25-epoxy-, (24R)-
[(1R)-3-[(2R)-3,3-dimethyloxiran-2-yl]-1-methyl-propyl]-tetramethyl-[?]one

2D Structure

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2D Structure of Epoxycycloartane-1

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 93.95% 97.25%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.88% 91.11%
CHEMBL2581 P07339 Cathepsin D 91.87% 98.95%
CHEMBL1937 Q92769 Histone deacetylase 2 91.10% 94.75%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.65% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.44% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.66% 97.09%
CHEMBL5103 Q969S8 Histone deacetylase 10 86.94% 90.08%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.90% 94.45%
CHEMBL3837 P07711 Cathepsin L 84.33% 96.61%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.16% 90.71%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.93% 100.00%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 80.69% 98.33%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 80.56% 93.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 80.39% 92.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Borrichia frutescens

Cross-Links

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PubChem 469544
LOTUS LTS0114369
wikiData Q105034356