ent-15beta-Angeloyloxy-7alpha,9alpha-dihydroxy-kaur-16-en-19-oic acid

Details

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Internal ID 91efdfea-a664-425b-b7cb-a418d90fb9cd
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Kaurane diterpenoids
IUPAC Name (1R,2S,4S,5R,9R,10R,13R,15S)-2,10-dihydroxy-5,9-dimethyl-15-[(Z)-2-methylbut-2-enoyl]oxy-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C25H36O6/c1-6-14(2)20(27)31-19-15(3)16-8-11-25(30)23(5)10-7-9-22(4,21(28)29)17(23)12-18(26)24(19,25)13-16/h6,16-19,26,30H,3,7-13H2,1-2,4-5H3,(H,28,29)/b14-6-/t16-,17-,18+,19+,22-,23-,24-,25-/m1/s1
InChI Key YOTJIOFPPBIQPT-DCYNMUGFSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C25H36O6
Molecular Weight 432.50 g/mol
Exact Mass 432.25118886 g/mol
Topological Polar Surface Area (TPSA) 104.00 Ų
XlogP 2.90

Synonyms

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(5beta,7beta,8alpha,9beta,10alpha,13alpha,15alpha)-7,9-dihydroxy-15-{[(2Z)-2-methylbut-2-enoyl]oxy}kaur-16-en-18-oic acid
InChI=1/C25H36O6/c1-6-14(2)20(27)31-19-15(3)16-8-11-25(30)23(5)10-7-9-22(4,21(28)29)17(23)12-18(26)24(19,25)13-16/h6,16-19,26,30H,3,7-13H2,1-2,4-5H3,(H,28,29)/b14-6-/t16?,17-,18+,19+,22-,23-,24-,25-/m1/s

2D Structure

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2D Structure of ent-15beta-Angeloyloxy-7alpha,9alpha-dihydroxy-kaur-16-en-19-oic acid

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 89.90% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 88.98% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.55% 96.09%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 87.51% 93.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.20% 95.56%
CHEMBL340 P08684 Cytochrome P450 3A4 86.36% 91.19%
CHEMBL2581 P07339 Cathepsin D 86.24% 98.95%
CHEMBL4227 P25090 Lipoxin A4 receptor 85.46% 100.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.42% 89.00%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 84.92% 82.69%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.48% 100.00%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 83.53% 95.50%
CHEMBL1937 Q92769 Histone deacetylase 2 83.41% 94.75%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 82.30% 96.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 82.02% 97.25%
CHEMBL241 Q14432 Phosphodiesterase 3A 81.88% 92.94%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 81.67% 91.07%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.65% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 81.62% 97.09%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.31% 99.23%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 80.68% 95.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Oyedaea verbesinoides

Cross-Links

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PubChem 643679
LOTUS LTS0127351
wikiData Q105351516