Emericellamide A

Details

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Internal ID ba854fbd-c7ad-4dde-a45c-ded08d4b97f5
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (3S,6S,9S,12S,18R,19R)-3,6,18-trimethyl-9-(2-methylpropyl)-19-[(2S)-octan-2-yl]-12-propan-2-yl-1-oxa-4,7,10,13,16-pentazacyclononadecane-2,5,8,11,14,17-hexone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C31H55N5O7/c1-10-11-12-13-14-19(6)26-20(7)27(38)32-16-24(37)36-25(18(4)5)30(41)35-23(15-17(2)3)29(40)33-21(8)28(39)34-22(9)31(42)43-26/h17-23,25-26H,10-16H2,1-9H3,(H,32,38)(H,33,40)(H,34,39)(H,35,41)(H,36,37)/t19-,20+,21-,22-,23-,25-,26+/m0/s1
InChI Key QURRTAYEASAREY-OOVPVTRWSA-N
Popularity 6 references in papers

Physical and Chemical Properties

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Molecular Formula C31H55N5O7
Molecular Weight 609.80 g/mol
Exact Mass 609.41014911 g/mol
Topological Polar Surface Area (TPSA) 172.00 Ų
XlogP 4.90

Synonyms

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CHEBI:64373
(3S,6S,9S,12S,18R,19R)-3,6,18-trimethyl-9-(2-methylpropyl)-19-[(2S)-octan-2-yl]-12-(propan-2-yl)-1-oxa-4,7,10,13,16-pentaazacyclononadecane-2,5,8,11,14,17-hexone
(3S,6S,9S,12S,18R,19R)-3,6,18-trimethyl-9-(2-methylpropyl)-19-((2S)-octan-2-yl)-12-(propan-2-yl)-1-oxa-4,7,10,13,16-pentaazacyclononadecane-2,5,8,11,14,17-hexone
RefChem:136628
(3S,6S,9S,12S,18R,19R)-3,6,18-trimethyl-9-(2-methylpropyl)-19-((2S)-octan-2-yl)-12-propan-2-yl-1-oxa-4,7,10,13,16-pentazacyclononadecane-2,5,8,11,14,17-hexone
CHEMBL225269
Q27133243

2D Structure

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2D Structure of Emericellamide A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL230 P35354 Cyclooxygenase-2 98.81% 89.63%
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.70% 97.25%
CHEMBL2581 P07339 Cathepsin D 98.34% 98.95%
CHEMBL5103 Q969S8 Histone deacetylase 10 96.60% 90.08%
CHEMBL1949 P62937 Cyclophilin A 94.72% 98.57%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.53% 96.09%
CHEMBL2996 Q05655 Protein kinase C delta 92.51% 97.79%
CHEMBL4588 P22894 Matrix metalloproteinase 8 92.02% 94.66%
CHEMBL4462 Q8IXJ6 NAD-dependent deacetylase sirtuin 2 91.99% 90.24%
CHEMBL321 P14780 Matrix metalloproteinase 9 91.69% 92.12%
CHEMBL3310 Q96DB2 Histone deacetylase 11 91.57% 88.56%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 90.97% 91.11%
CHEMBL4040 P28482 MAP kinase ERK2 89.66% 83.82%
CHEMBL1937 Q92769 Histone deacetylase 2 89.56% 94.75%
CHEMBL3401 O75469 Pregnane X receptor 88.52% 94.73%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 87.94% 91.81%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 87.90% 93.10%
CHEMBL299 P17252 Protein kinase C alpha 87.86% 98.03%
CHEMBL3359 P21462 Formyl peptide receptor 1 87.82% 93.56%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.23% 90.71%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 87.03% 97.64%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.39% 94.45%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 85.75% 96.11%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 85.45% 97.29%
CHEMBL3060 Q9Y345 Glycine transporter 2 85.38% 99.17%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 84.53% 95.00%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 84.52% 96.90%
CHEMBL255 P29275 Adenosine A2b receptor 84.38% 98.59%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 84.33% 100.00%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 84.09% 96.47%
CHEMBL4105838 Q96GG9 DCN1-like protein 1 83.11% 95.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.07% 97.09%
CHEMBL3192 Q9BY41 Histone deacetylase 8 82.70% 93.99%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.66% 100.00%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 81.84% 95.50%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 81.74% 91.71%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 81.73% 96.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 81.54% 93.00%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 81.22% 92.08%
CHEMBL1907 P15144 Aminopeptidase N 80.87% 93.31%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 80.78% 89.34%
CHEMBL3524 P56524 Histone deacetylase 4 80.65% 92.97%
CHEMBL4616 Q92847 Ghrelin receptor 80.53% 92.00%
CHEMBL4803 P29474 Nitric-oxide synthase, endothelial 80.26% 86.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 16216151
LOTUS LTS0079254
wikiData Q27133243