Epelmycin A

Details

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Internal ID 4685483e-5ca2-425c-a0e7-c43b6b5509e8
Taxonomy Phenylpropanoids and polyketides > Anthracyclines
IUPAC Name methyl (1S,2R,4S)-4-[(2S,4R,5S,6S)-4-(dimethylamino)-6-methyl-5-[(2S,5S,6S)-6-methyl-5-[(2R,6S)-6-methyl-5-oxooxan-2-yl]oxyoxan-2-yl]oxyoxan-2-yl]oxy-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C42H53NO15/c1-8-42(51)17-26(31-32(35(42)41(50)52-7)39(49)33-34(38(31)48)37(47)30-21(36(33)46)10-9-11-24(30)45)57-29-16-22(43(5)6)40(20(4)55-29)58-28-15-13-25(19(3)54-28)56-27-14-12-23(44)18(2)53-27/h9-11,18-20,22,25-29,35,40,45,48-49,51H,8,12-17H2,1-7H3/t18-,19-,20-,22+,25-,26-,27-,28-,29+,35+,40+,42+/m0/s1
InChI Key GSCMQULDSZTLKO-NFDDGJDISA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C42H53NO15
Molecular Weight 811.90 g/mol
Exact Mass 811.34151998 g/mol
Topological Polar Surface Area (TPSA) 217.00 Ų
XlogP 5.00

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Epelmycin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.60% 91.11%
CHEMBL2581 P07339 Cathepsin D 99.09% 98.95%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 97.34% 96.38%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.75% 96.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 94.97% 89.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 94.84% 99.23%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.49% 97.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.40% 95.56%
CHEMBL261 P00915 Carbonic anhydrase I 90.42% 96.76%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.47% 95.89%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 88.59% 92.62%
CHEMBL226 P30542 Adenosine A1 receptor 86.69% 95.93%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 85.61% 96.21%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 84.87% 85.14%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 84.47% 83.00%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 84.43% 85.11%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.39% 99.17%
CHEMBL253 P34972 Cannabinoid CB2 receptor 84.21% 97.25%
CHEMBL340 P08684 Cytochrome P450 3A4 83.99% 91.19%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.56% 93.03%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 83.36% 97.33%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 82.90% 92.88%
CHEMBL241 Q14432 Phosphodiesterase 3A 82.87% 92.94%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 82.72% 96.00%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 82.65% 94.33%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.46% 94.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.34% 97.14%
CHEMBL4208 P20618 Proteasome component C5 82.30% 90.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.48% 100.00%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 80.61% 96.67%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 80.11% 96.77%
CHEMBL3359 P21462 Formyl peptide receptor 1 80.04% 93.56%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139589246
LOTUS LTS0021985
wikiData Q104402086