Sulfurmycin E

Details

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Internal ID 704b0ae7-e222-4342-a6e7-db6ba546fd14
Taxonomy Phenylpropanoids and polyketides > Anthracyclines
IUPAC Name methyl (1S,2R,4S)-4-[(2S,4S,5R,6S)-4-(dimethylamino)-5-[(2S,4S,5S,6S)-4-hydroxy-5-[(2S,5R,6S)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2,5,7-trihydroxy-6,11-dioxo-2-(2-oxopropyl)-3,4-dihydro-1H-tetracene-1-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C43H55NO16/c1-18(45)16-43(53)17-29(34-23(36(43)42(52)54-7)13-24-35(39(34)51)38(50)33-22(37(24)49)9-8-10-27(33)47)58-31-14-25(44(5)6)40(20(3)56-31)60-32-15-28(48)41(21(4)57-32)59-30-12-11-26(46)19(2)55-30/h8-10,13,19-21,25-26,28-32,36,40-41,46-48,51,53H,11-12,14-17H2,1-7H3/t19-,20-,21-,25-,26+,28-,29-,30-,31+,32-,36+,40-,41+,43-/m0/s1
InChI Key ONRDFNTYASFICP-SNSWQSRASA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C43H55NO16
Molecular Weight 841.90 g/mol
Exact Mass 841.35208467 g/mol
Topological Polar Surface Area (TPSA) 237.00 Ų
XlogP 2.60

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Sulfurmycin E

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.86% 91.11%
CHEMBL2581 P07339 Cathepsin D 99.12% 98.95%
CHEMBL1806 P11388 DNA topoisomerase II alpha 98.36% 89.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.92% 85.14%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 97.46% 96.38%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.29% 96.09%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 93.60% 99.23%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.51% 97.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.33% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.94% 86.33%
CHEMBL226 P30542 Adenosine A1 receptor 92.34% 95.93%
CHEMBL340 P08684 Cytochrome P450 3A4 92.32% 91.19%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 92.12% 96.21%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 91.51% 92.62%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.73% 95.89%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 88.26% 96.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 87.41% 100.00%
CHEMBL3401 O75469 Pregnane X receptor 87.03% 94.73%
CHEMBL4208 P20618 Proteasome component C5 86.96% 90.00%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 86.65% 95.83%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 84.02% 83.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.86% 94.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 82.57% 90.71%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 81.88% 96.67%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 81.65% 99.15%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 81.10% 91.07%
CHEMBL3060 Q9Y345 Glycine transporter 2 80.92% 99.17%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 80.82% 97.14%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 80.67% 97.50%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 80.48% 95.17%
CHEMBL1951 P21397 Monoamine oxidase A 80.43% 91.49%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139589067
LOTUS LTS0083965
wikiData Q105195075