Dnacin A1

Details

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Internal ID 8215c930-cc7f-4adf-8dde-79875127afe0
Taxonomy Organoheterocyclic compounds > Isoquinolines and derivatives > Isoquinoline quinones
IUPAC Name 13-amino-16-(hydroxymethyl)-20-methyl-11,14-dioxo-5-oxa-8,17,20-triazahexacyclo[15.3.1.03,19.04,8.09,18.010,15]henicosa-10(15),12-diene-21-carbonitrile
SMILES (Canonical) CN1C2CC3C1C4C(C5=C(C(N4C2C#N)CO)C(=O)C(=CC5=O)N)N6C3OCC6
SMILES (Isomeric) CN1C2CC3C1C4C(C5=C(C(N4C2C#N)CO)C(=O)C(=CC5=O)N)N6C3OCC6
InChI InChI=1S/C20H23N5O4/c1-23-10-4-8-16(23)18-17(24-2-3-29-20(8)24)15-13(27)5-9(22)19(28)14(15)12(7-26)25(18)11(10)6-21/h5,8,10-12,16-18,20,26H,2-4,7,22H2,1H3
InChI Key TWRFZLWJOXKOBK-UHFFFAOYSA-N
Popularity 7 references in papers

Physical and Chemical Properties

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Molecular Formula C20H23N5O4
Molecular Weight 397.40 g/mol
Exact Mass 397.17500423 g/mol
Topological Polar Surface Area (TPSA) 123.00 Ų
XlogP -1.80

Synonyms

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13-Amino-16-(hydroxymethyl)-20-methyl-11,14-dioxo-5-oxa-8,17,20-triazahexacyclo[15.3.1.03,19.04,8.09,18.010,15]henicosa-10(15),12-diene-21-carbonitrile
13-amino-16-(hydroxymethyl)-20-methyl-11,14-dioxo-5-oxa-8,17,20-triazahexacyclo(15.3.1.03,19.04,8.09,18.010,15)henicosa-10(15),12-diene-21-carbonitrile
RefChem:135333
SCHEMBL29884684
CHEBI:202558

2D Structure

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2D Structure of Dnacin A1

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL1978 P11511 Cytochrome P450 19A1 98.72% 91.76%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.75% 96.09%
CHEMBL2581 P07339 Cathepsin D 97.29% 98.95%
CHEMBL226 P30542 Adenosine A1 receptor 96.71% 95.93%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.03% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.72% 85.14%
CHEMBL2140 P48775 Tryptophan 2,3-dioxygenase 92.00% 98.46%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.14% 97.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.13% 95.56%
CHEMBL1871 P10275 Androgen Receptor 86.70% 96.43%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.95% 100.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.80% 89.00%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 84.25% 100.00%
CHEMBL3384 Q16512 Protein kinase N1 83.90% 80.71%
CHEMBL253 P34972 Cannabinoid CB2 receptor 83.50% 97.25%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.64% 95.89%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 82.16% 94.80%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11741510
LOTUS LTS0084333
wikiData Q77372084