Disorazole-B1

Details

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Internal ID 35ef0d91-a71d-4985-af04-b50ed6d535f5
Taxonomy Organoheterocyclic compounds > Azoles > Oxazoles
IUPAC Name (2Z,4Z,9Z,19Z,21Z,26Z)-12,29-bis[(E)-3-hydroxy-2-methylhex-4-en-2-yl]-7,13,17,24,30,34-hexaoxa-35,36-diazapentacyclo[30.2.1.115,18.06,8.023,25]hexatriaconta-1(35),2,4,9,15,18(36),19,21,26,32-decaene-14,31-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C42H50N2O10/c1-7-15-33(45)41(3,4)35-21-13-19-31-29(51-31)17-9-12-24-38-44-28(26-50-38)40(48)54-36(42(5,6)34(46)16-8-2)22-14-20-32-30(52-32)18-10-11-23-37-43-27(25-49-37)39(47)53-35/h7-20,23-26,29-36,45-46H,21-22H2,1-6H3/b15-7+,16-8+,17-9-,18-10-,19-13-,20-14-,23-11-,24-12-
InChI Key FOQGKCOTKQAXPE-XIIYVMKPSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C42H50N2O10
Molecular Weight 742.90 g/mol
Exact Mass 742.34654580 g/mol
Topological Polar Surface Area (TPSA) 170.00 Ų
XlogP 7.60

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Disorazole-B1

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2039 P27338 Monoamine oxidase B 93.03% 92.51%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.05% 86.33%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 90.89% 91.11%
CHEMBL3401 O75469 Pregnane X receptor 90.83% 94.73%
CHEMBL230 P35354 Cyclooxygenase-2 90.42% 89.63%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 90.24% 85.14%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.22% 97.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.25% 99.23%
CHEMBL2581 P07339 Cathepsin D 88.00% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.71% 95.56%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 86.70% 100.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 83.01% 99.17%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 82.60% 93.65%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 81.70% 96.09%
CHEMBL3137262 O60341 LSD1/CoREST complex 80.75% 97.09%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.52% 93.03%
CHEMBL4662 P28074 Proteasome Macropain subunit MB1 80.47% 93.85%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 20786764
LOTUS LTS0176763
wikiData Q77572723