4-Hydroxy-6-(methoxycarbonyl)-2-methyl-3a,4,5,7a-tetrahydro-2H-1,3-benzodioxole-2-carboximidic acid

Details

Top
Internal ID cd43d6f3-4b89-4d1a-b794-a15ef7bb9243
Taxonomy Organic oxygen compounds > Organooxygen compounds > Ethers > Acetals > Ketals
IUPAC Name methyl (2S,3aR,7aR)-2-carbamoyl-7-hydroxy-2-methyl-3a,6,7,7a-tetrahydro-1,3-benzodioxole-5-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C11H15NO6/c1-11(10(12)15)17-7-4-5(9(14)16-2)3-6(13)8(7)18-11/h4,6-8,13H,3H2,1-2H3,(H2,12,15)/t6?,7-,8-,11+/m1/s1
InChI Key SHAXHGRARCZUPJ-YEHZVILMSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

Top
Molecular Formula C11H15NO6
Molecular Weight 257.24 g/mol
Exact Mass 257.08993720 g/mol
Topological Polar Surface Area (TPSA) 108.00 Ų
XlogP -1.30

Synonyms

Top
4-Hydroxy-6-(methoxycarbonyl)-2-methyl-3a,4,5,7a-tetrahydro-2H-1,3-benzodioxole-2-carboximidic acid
RefChem:1070798
DTXCID701348658
methyl (2S,3aR,7aR)-2-carbamoyl-7-hydroxy-2-methyl-3a,6,7,7a-tetrahydro-1,3-benzodioxole-5-carboxylate
1,3-Benzodioxole-5-carboxylic acid, 3a,6,7,7a-tetrahydro-2-(aminocarbonyl)-7-hydroxy-2-methyl-, methyl ester, (2S-(2-alpha,3a-alpha,7-alpha,7a-beta))-
(2S,3aR,7aR)-4-Hydroxy-6-(methoxycarbonyl)-2-methyl-3a,4,5,7a-tetrahydro-2H-1,3-benzodioxole-2-carboximidic acid

2D Structure

Top
2D Structure of 4-Hydroxy-6-(methoxycarbonyl)-2-methyl-3a,4,5,7a-tetrahydro-2H-1,3-benzodioxole-2-carboximidic acid

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.77% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.24% 96.09%
CHEMBL4040 P28482 MAP kinase ERK2 93.79% 83.82%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 90.81% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 87.56% 85.14%
CHEMBL340 P08684 Cytochrome P450 3A4 86.09% 91.19%
CHEMBL221 P23219 Cyclooxygenase-1 85.91% 90.17%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.68% 97.09%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.84% 95.89%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.71% 86.33%
CHEMBL5028 O14672 ADAM10 81.45% 97.50%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 80.50% 91.07%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 124640
LOTUS LTS0072715
wikiData Q82892305