Dinklagin A

Details

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Internal ID 4cda5c7d-2ea0-435c-ace4-5cf0ca9b6fc2
Taxonomy Phenylpropanoids and polyketides > Flavonoids > Flavans > 6-prenylated flavans > 6-prenylated flavanones
IUPAC Name (2S)-2-(2,2-dimethylchromen-6-yl)-7-hydroxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
SMILES (Canonical) CC(=CCC1=CC2=C(C=C1O)OC(CC2=O)C3=CC4=C(C=C3)OC(C=C4)(C)C)C
SMILES (Isomeric) CC(=CCC1=CC2=C(C=C1O)O[C@@H](CC2=O)C3=CC4=C(C=C3)OC(C=C4)(C)C)C
InChI InChI=1S/C25H26O4/c1-15(2)5-6-16-12-19-21(27)14-23(28-24(19)13-20(16)26)17-7-8-22-18(11-17)9-10-25(3,4)29-22/h5,7-13,23,26H,6,14H2,1-4H3/t23-/m0/s1
InChI Key XPMXYEFQBQWMEC-QHCPKHFHSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C25H26O4
Molecular Weight 390.50 g/mol
Exact Mass 390.18310931 g/mol
Topological Polar Surface Area (TPSA) 55.80 Ų
XlogP 5.40

Synonyms

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487010-46-8
(2S)-2-(2,2-dimethylchromen-6-yl)-7-hydroxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
7-Hydroxy-6-prenyl-6'',6''-dimethylpyrano[2'',3'':4',3']flavanone
6-(3,3-dimethylallyl)-7-hydroxy-6''', 6'''-dimethylchromeno-(4',3',2''',3''')-flavanone
7-Hydroxy-6-prenyl-6'',6''-dimethylpyrano(2'',3'':4',3')flavanone
RefChem:134459
(-)-6-(3,3-Dimethylallyl)-7-hydroxy-6''', 6'''-dimethylchromeno-(4',3',2''',3''')-flavanone
DTXSID90964102
LMPK12140057
(2S)-7-Hydroxy-2',2'-dimethyl-6-(3-methylbut-2-en-1-yl)-2,3-dihydro-2'H,4H-[2,6'-bi-1-benzopyran]-4-one
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Dinklagin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.52% 91.11%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 98.92% 85.14%
CHEMBL2581 P07339 Cathepsin D 97.13% 98.95%
CHEMBL1951 P21397 Monoamine oxidase A 95.16% 91.49%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.92% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.17% 94.45%
CHEMBL1806 P11388 DNA topoisomerase II alpha 92.58% 89.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.45% 97.09%
CHEMBL1994 P08235 Mineralocorticoid receptor 91.44% 100.00%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 91.15% 93.40%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.01% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.91% 95.89%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.14% 95.56%
CHEMBL3401 O75469 Pregnane X receptor 86.39% 94.73%
CHEMBL4145 Q9UKV0 Histone deacetylase 9 84.86% 85.49%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 84.03% 92.62%
CHEMBL4208 P20618 Proteasome component C5 83.97% 90.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.36% 99.23%
CHEMBL2039 P27338 Monoamine oxidase B 81.02% 92.51%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 80.94% 94.80%
CHEMBL3922 P50579 Methionine aminopeptidase 2 80.53% 97.28%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Dorstenia dinklagei

Cross-Links

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PubChem 636494
LOTUS LTS0052759
wikiData Q82946020