Dihydrospumigin N

Details

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Internal ID 8010e39c-4680-4c83-afac-fb84420374f3
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Dipeptides
IUPAC Name (2S)-N-[(2S)-5-(diaminomethylideneamino)-1-hydroxypentan-2-yl]-1-[(2R)-2-[[2-hydroxy-4-(4-hydroxyphenyl)butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H42N6O7/c31-30(32)33-15-1-3-21(18-37)34-27(41)25-4-2-16-36(25)29(43)24(17-20-7-12-23(39)13-8-20)35-28(42)26(40)14-9-19-5-10-22(38)11-6-19/h5-8,10-13,21,24-26,37-40H,1-4,9,14-18H2,(H,34,41)(H,35,42)(H4,31,32,33)/t21-,24+,25-,26?/m0/s1
InChI Key WKADCTRDFMBYPU-FDHYGZKMSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C30H42N6O7
Molecular Weight 598.70 g/mol
Exact Mass 598.31149770 g/mol
Topological Polar Surface Area (TPSA) 224.00 Ų
XlogP 0.50

Synonyms

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CHEMBL4176114
DTXSID901186911
BDBM50277986

2D Structure

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2D Structure of Dihydrospumigin N

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.01% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.86% 96.09%
CHEMBL3837 P07711 Cathepsin L 97.26% 96.61%
CHEMBL2514 O95665 Neurotensin receptor 2 97.01% 100.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.74% 94.45%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 96.59% 98.33%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 96.19% 96.67%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.86% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 95.84% 97.09%
CHEMBL1255126 O15151 Protein Mdm4 95.61% 90.20%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 94.81% 100.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 94.33% 95.89%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 93.97% 91.81%
CHEMBL233 P35372 Mu opioid receptor 93.60% 97.93%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 93.08% 90.71%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 93.04% 97.64%
CHEMBL3060 Q9Y345 Glycine transporter 2 91.86% 99.17%
CHEMBL340 P08684 Cytochrome P450 3A4 91.71% 91.19%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 91.48% 96.03%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.36% 95.89%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 91.24% 100.00%
CHEMBL4361 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 91.14% 95.52%
CHEMBL4123 P30989 Neurotensin receptor 1 91.07% 96.67%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 90.43% 93.10%
CHEMBL4198 P98170 Inhibitor of apoptosis protein 3 90.11% 97.79%
CHEMBL4588 P22894 Matrix metalloproteinase 8 89.62% 94.66%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 89.41% 100.00%
CHEMBL4227 P25090 Lipoxin A4 receptor 89.37% 100.00%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 89.32% 96.95%
CHEMBL249 P25103 Neurokinin 1 receptor 89.00% 99.17%
CHEMBL3437 Q16853 Amine oxidase, copper containing 88.12% 94.00%
CHEMBL236 P41143 Delta opioid receptor 86.96% 99.35%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 86.81% 82.69%
CHEMBL2535 P11166 Glucose transporter 85.75% 98.75%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 85.44% 97.21%
CHEMBL259 P32245 Melanocortin receptor 4 84.74% 95.38%
CHEMBL4101 P17612 cAMP-dependent protein kinase alpha-catalytic subunit 84.07% 82.86%
CHEMBL2319 P06870 Kallikrein 1 83.97% 90.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 83.33% 95.56%
CHEMBL3359 P21462 Formyl peptide receptor 1 82.87% 93.56%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.49% 93.00%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 82.48% 95.00%
CHEMBL2327 P21452 Neurokinin 2 receptor 82.41% 98.89%
CHEMBL5261 Q7L7X3 Serine/threonine-protein kinase TAO1 81.69% 89.33%
CHEMBL206 P03372 Estrogen receptor alpha 80.66% 97.64%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 145974544
LOTUS LTS0198632
wikiData Q105307163