Dihydropalmatine

Details

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Internal ID 808bdb8e-8845-45bc-96fd-30a758a9b711
Taxonomy Alkaloids and derivatives > Protoberberine alkaloids and derivatives
IUPAC Name 2,3,9,10-tetramethoxy-6,8-dihydro-5H-isoquinolino[2,1-b]isoquinoline
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H23NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,9-11H,7-8,12H2,1-4H3
InChI Key PTPHDVKWAYIFRX-UHFFFAOYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C21H23NO4
Molecular Weight 353.40 g/mol
Exact Mass 353.16270821 g/mol
Topological Polar Surface Area (TPSA) 40.20 Ų
XlogP 3.70

Synonyms

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26067-60-7
2,3,9,10-tetramethoxy-6,8-dihydro-5H-isoquinolino[2,1-b]isoquinoline
SCHEMBL12329651
HY-N4240
AKOS037515270
MS-25491
CS-0032498
E87112

2D Structure

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2D Structure of Dihydropalmatine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5747 Q92793 CREB-binding protein 96.72% 95.12%
CHEMBL1951 P21397 Monoamine oxidase A 95.03% 91.49%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.03% 96.09%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 94.74% 93.40%
CHEMBL1293249 Q13887 Kruppel-like factor 5 94.53% 86.33%
CHEMBL2535 P11166 Glucose transporter 93.12% 98.75%
CHEMBL3192 Q9BY41 Histone deacetylase 8 92.31% 93.99%
CHEMBL2581 P07339 Cathepsin D 90.22% 98.95%
CHEMBL2146302 O94925 Glutaminase kidney isoform, mitochondrial 88.99% 100.00%
CHEMBL4208 P20618 Proteasome component C5 88.51% 90.00%
CHEMBL2056 P21728 Dopamine D1 receptor 87.57% 91.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.50% 95.89%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 86.04% 95.56%
CHEMBL5925 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 83.32% 92.38%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.06% 94.00%
CHEMBL3746 P80365 11-beta-hydroxysteroid dehydrogenase 2 80.83% 94.78%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 80.65% 82.67%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 80.37% 89.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Thalictrum foliolosum

Cross-Links

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PubChem 1023495
LOTUS LTS0094925
wikiData Q105214805