Desertomycin A

Details

Top
Internal ID 00b45e9d-0c4e-4674-b8d8-e591983c0e43
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name 42-(6-amino-3-hydroxyhexan-2-yl)-8,10,16,20,24,26,28,30,32,34,36,38-dodecahydroxy-3,7,9,15,19,21,31,33-octamethyl-23-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1-oxacyclodotetraconta-3,13,17,21,39-pentaen-2-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C61H109NO21/c1-32-15-10-11-19-47(70)38(7)55(75)33(2)16-12-17-35(4)60(80)81-51(37(6)46(69)20-14-24-62)21-13-18-41(64)26-42(65)28-48(71)39(8)56(76)40(9)49(72)29-43(66)27-44(67)30-50(73)52(25-36(5)54(74)34(3)22-23-45(32)68)82-61-59(79)58(78)57(77)53(31-63)83-61/h10,13,15,17-18,22-23,25,32-34,37-59,61,63-79H,11-12,14,16,19-21,24,26-31,62H2,1-9H3/t32?,33?,34?,37?,38?,39?,40?,41?,42?,43?,44?,45?,46?,47?,48?,49?,50?,51?,52?,53-,54?,55?,56?,57-,58+,59+,61+/m1/s1
InChI Key FKPDQSQJNFFSAS-BURXMLRQSA-N
Popularity 4 references in papers

Physical and Chemical Properties

Top
Molecular Formula C61H109NO21
Molecular Weight 1192.50 g/mol
Exact Mass 1191.74920949 g/mol
Topological Polar Surface Area (TPSA) 415.00 Ų
XlogP 1.20

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of Desertomycin A

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.22% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.18% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.71% 96.09%
CHEMBL3137262 O60341 LSD1/CoREST complex 97.52% 97.09%
CHEMBL2581 P07339 Cathepsin D 96.96% 98.95%
CHEMBL4581 P52732 Kinesin-like protein 1 95.41% 93.18%
CHEMBL3714130 P46095 G-protein coupled receptor 6 95.23% 97.36%
CHEMBL3401 O75469 Pregnane X receptor 92.16% 94.73%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 90.20% 96.47%
CHEMBL3359 P21462 Formyl peptide receptor 1 89.65% 93.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.63% 89.00%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 87.99% 95.89%
CHEMBL6136 O60341 Lysine-specific histone demethylase 1 87.43% 95.58%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.73% 95.89%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.02% 86.33%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.62% 99.17%
CHEMBL4227 P25090 Lipoxin A4 receptor 83.93% 100.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.88% 100.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.68% 94.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 83.60% 85.14%
CHEMBL5255 O00206 Toll-like receptor 4 83.56% 92.50%
CHEMBL3038469 P24941 CDK2/Cyclin A 83.17% 91.38%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 82.64% 96.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 82.29% 95.56%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 82.04% 95.50%
CHEMBL2996 Q05655 Protein kinase C delta 80.83% 97.79%
CHEMBL2514 O95665 Neurotensin receptor 2 80.48% 100.00%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 101616447
LOTUS LTS0207912
wikiData Q104996726