Deoxytubulosine

Details

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Internal ID 83da391c-5509-44d1-bd7e-792346996c3c
Taxonomy Alkaloids and derivatives > Harmala alkaloids
IUPAC Name (2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2-[[(1R)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C29H37N3O2/c1-4-18-17-32-12-10-19-15-27(33-2)28(34-3)16-23(19)26(32)14-20(18)13-25-29-22(9-11-30-25)21-7-5-6-8-24(21)31-29/h5-8,15-16,18,20,25-26,30-31H,4,9-14,17H2,1-3H3/t18-,20-,25+,26-/m0/s1
InChI Key AVJZNOIWPGXYKM-LXFCCGDJSA-N
Popularity 7 references in papers

Physical and Chemical Properties

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Molecular Formula C29H37N3O2
Molecular Weight 459.60 g/mol
Exact Mass 459.28857743 g/mol
Topological Polar Surface Area (TPSA) 49.50 Ų
XlogP 5.00

Synonyms

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10,11-Dimethoxytubulosan
2632-30-6
Tubulosan, 10,11-dimethoxy-
C11817
(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2-[[(1R)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine
2H-Benzo[a]quinolizine, 3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-, (2S,3R,11bS)-
AC1L4VWR
AC1Q56PD
CHEBI:4433
CHEMBL4212545
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Deoxytubulosine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.00% 96.09%
CHEMBL3192 Q9BY41 Histone deacetylase 8 97.30% 93.99%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.48% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.43% 94.45%
CHEMBL2581 P07339 Cathepsin D 93.45% 98.95%
CHEMBL2535 P11166 Glucose transporter 93.11% 98.75%
CHEMBL241 Q14432 Phosphodiesterase 3A 92.99% 92.94%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.50% 97.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.46% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.71% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.08% 86.33%
CHEMBL228 P31645 Serotonin transporter 88.08% 95.51%
CHEMBL1914 P06276 Butyrylcholinesterase 88.01% 95.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 87.33% 92.62%
CHEMBL217 P14416 Dopamine D2 receptor 86.03% 95.62%
CHEMBL4302 P08183 P-glycoprotein 1 85.74% 92.98%
CHEMBL253 P34972 Cannabinoid CB2 receptor 85.52% 97.25%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 84.22% 82.38%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.98% 95.89%
CHEMBL255 P29275 Adenosine A2b receptor 83.14% 98.59%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 82.69% 89.62%
CHEMBL5747 Q92793 CREB-binding protein 82.25% 95.12%
CHEMBL5925 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 81.18% 92.38%
CHEMBL3060 Q9Y345 Glycine transporter 2 80.74% 99.17%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 80.04% 94.08%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 80.02% 94.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 165003
LOTUS LTS0104122
wikiData Q27106381