Deoxydynemicin A

Details

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Internal ID 4098ed7e-ddba-48fa-83d8-a3b73bf70584
Taxonomy Benzenoids > Anthracenes > Anthraquinones
IUPAC Name (11Z)-21,28-dihydroxy-7-methoxy-5-methyl-19,26-dioxo-3-oxa-16-azaheptacyclo[15.12.0.02,4.02,8.04,15.018,27.020,25]nonacosa-1(29),6,11,17,20(25),21,23,27-octaen-9,13-diyne-6-carboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H19NO8/c1-13-20(28(36)37)27(38-2)15-9-5-3-4-6-11-19-29(13)30(15,39-29)16-12-18(33)22-23(24(16)31-19)26(35)21-14(25(22)34)8-7-10-17(21)32/h3-4,7-8,10,12-13,15,19,31-33H,1-2H3,(H,36,37)/b4-3-
InChI Key RVUGUFLMKMPZBW-ARJAWSKDSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C30H19NO8
Molecular Weight 521.50 g/mol
Exact Mass 521.11106656 g/mol
Topological Polar Surface Area (TPSA) 146.00 Ų
XlogP 3.60

Synonyms

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130640-33-4
(11Z)-21,28-dihydroxy-7-methoxy-5-methyl-19,26-dioxo-3-oxa-16-azaheptacyclo[15.12.0.02,4.02,8.04,15.018,27.020,25]nonacosa-1(29),6,11,17,20(25),21,23,27-octaen-9,13-diyne-6-carboxylic acid

2D Structure

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2D Structure of Deoxydynemicin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.32% 91.11%
CHEMBL1966 Q02127 Dihydroorotate dehydrogenase 97.94% 96.09%
CHEMBL2581 P07339 Cathepsin D 97.50% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.38% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.83% 96.09%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 92.40% 99.15%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 92.25% 99.23%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.15% 86.33%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 88.65% 93.03%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 85.34% 96.38%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.32% 89.00%
CHEMBL340 P08684 Cytochrome P450 3A4 85.07% 91.19%
CHEMBL1937 Q92769 Histone deacetylase 2 84.92% 94.75%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.77% 90.71%
CHEMBL3401 O75469 Pregnane X receptor 84.60% 94.73%
CHEMBL2146302 O94925 Glutaminase kidney isoform, mitochondrial 84.31% 100.00%
CHEMBL4208 P20618 Proteasome component C5 81.32% 90.00%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 80.97% 96.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 80.20% 94.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 6444006
LOTUS LTS0084821
wikiData Q105246324