Deoliosyl-3C-|A-L-digitoxosyl-MTM

Details

Top
Internal ID ea4b6c90-e9fc-424b-b342-d72653040469
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbohydrates and carbohydrate conjugates > Oligosaccharides
IUPAC Name (2S,3S)-2-[(2S,4R,5R,6R)-4-[(2S,4R,5S,6S)-4-[(2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-6-[(2S,4R,5R,6R)-4-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-8,9-dihydroxy-7-methyl-3,4-dihydro-2H-anthracen-1-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C52H76O24/c1-18-29(72-34-14-30(43(58)21(4)68-34)73-33-13-28(54)42(57)20(3)67-33)12-26-10-25-11-27(49(66-9)48(63)41(56)19(2)53)50(47(62)39(25)46(61)38(26)40(18)55)76-36-16-31(44(59)23(6)70-36)74-35-15-32(45(60)22(5)69-35)75-37-17-52(8,65)51(64)24(7)71-37/h10,12,19-24,27-28,30-37,41-45,49-51,53-61,64-65H,11,13-17H2,1-9H3/t19-,20-,21-,22+,23-,24-,27+,28-,30-,31-,32-,33+,34+,35+,36+,37+,41+,42-,43-,44-,45+,49+,50+,51-,52+/m1/s1
InChI Key CFCUWKMKBJTWLW-ALHYKVOTSA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C52H76O24
Molecular Weight 1085.10 g/mol
Exact Mass 1084.47265329 g/mol
Topological Polar Surface Area (TPSA) 358.00 Ų
XlogP 0.60

Synonyms

Top
CHEMBL255884
HY-145717
CS-0380027
Deoliosyl-3C-alpha-L-digitoxosyl-mithramycin

2D Structure

Top
2D Structure of Deoliosyl-3C-|A-L-digitoxosyl-MTM

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 99.43% 85.14%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.65% 91.11%
CHEMBL2581 P07339 Cathepsin D 96.59% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.43% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.72% 94.45%
CHEMBL1806 P11388 DNA topoisomerase II alpha 94.08% 89.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 93.87% 90.71%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 93.85% 94.00%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 93.71% 91.03%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 93.53% 96.95%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 93.42% 99.23%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.73% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.17% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 91.92% 95.89%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 88.07% 95.50%
CHEMBL2535 P11166 Glucose transporter 87.92% 98.75%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 87.50% 91.07%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 87.13% 97.21%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 87.00% 96.21%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.85% 97.09%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 86.68% 85.11%
CHEMBL220 P22303 Acetylcholinesterase 86.21% 94.45%
CHEMBL2413 P32246 C-C chemokine receptor type 1 86.07% 89.50%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.58% 97.14%
CHEMBL4302 P08183 P-glycoprotein 1 84.49% 92.98%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.62% 100.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 82.61% 93.03%
CHEMBL340 P08684 Cytochrome P450 3A4 81.90% 91.19%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 80.91% 99.15%
CHEMBL2345 P51812 Ribosomal protein S6 kinase alpha 3 80.46% 95.64%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 80.30% 95.89%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 24799685
LOTUS LTS0084603
wikiData Q104956346