Dendroamide B

Details

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Internal ID c8cf1318-28a1-4009-82ac-2bd0b0a1dc45
Taxonomy Phenylpropanoids and polyketides > Macrolactams
IUPAC Name (4R,11R,18R)-4,7,11-trimethyl-18-(2-methylsulfanylethyl)-6-oxa-13,20-dithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.15,8.112,15]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H24N6O4S3/c1-9-19-27-15(11(3)31-19)18(30)23-10(2)20-25-14(7-33-20)17(29)24-12(5-6-32-4)21-26-13(8-34-21)16(28)22-9/h7-10,12H,5-6H2,1-4H3,(H,22,28)(H,23,30)(H,24,29)/t9-,10-,12-/m1/s1
InChI Key AERWTVOXUHXGAE-CKYFFXLPSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C21H24N6O4S3
Molecular Weight 520.70 g/mol
Exact Mass 520.10211679 g/mol
Topological Polar Surface Area (TPSA) 221.00 Ų
XlogP 2.10

Synonyms

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MLS005148192
CHEMBL462762
SCHEMBL16431329
DTXSID401046306
SMR003965427

2D Structure

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2D Structure of Dendroamide B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL230 P35354 Cyclooxygenase-2 96.32% 89.63%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 94.27% 94.00%
CHEMBL1293277 O15118 Niemann-Pick C1 protein 93.46% 81.11%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 92.53% 89.34%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.14% 99.23%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 90.85% 85.14%
CHEMBL2850 P49840 Glycogen synthase kinase-3 alpha 90.49% 88.84%
CHEMBL2581 P07339 Cathepsin D 90.23% 98.95%
CHEMBL4439 P36897 TGF-beta receptor type I 86.99% 98.16%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.19% 86.33%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 86.10% 93.03%
CHEMBL3401 O75469 Pregnane X receptor 85.54% 94.73%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 84.11% 96.67%
CHEMBL1937 Q92769 Histone deacetylase 2 83.39% 94.75%
CHEMBL255 P29275 Adenosine A2b receptor 82.68% 98.59%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 82.47% 85.11%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 82.30% 93.65%
CHEMBL2243 O00519 Anandamide amidohydrolase 82.27% 97.53%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 81.84% 95.56%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.34% 90.71%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 80.56% 92.68%
CHEMBL2717 Q9HCR9 Phosphodiesterase 11A 80.50% 85.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10673550
LOTUS LTS0230283
wikiData Q105275256