Delftibactin B

Details

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Internal ID a7f5f4f0-ac06-467f-945f-396cd1704bc0
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name 4-[[1-[[2-[[(Z)-1-[[5-[acetyl(hydroxy)amino]-1-[[1-[[5-(diaminomethylideneamino)-1-[(1-hydroxy-2-oxopiperidin-3-yl)amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxobut-2-en-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-[(4-amino-3-hydroxy-2-methylpentanoyl)amino]-2-hydroxy-4-oxobutanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C41H70N14O18/c1-6-22(47-27(59)16-46-37(67)28(20(4)57)52-38(68)29(31(61)40(70)71)53-32(62)18(2)30(60)19(3)42)33(63)48-24(11-8-14-54(72)21(5)58)35(65)51-26(17-56)36(66)49-23(10-7-13-45-41(43)44)34(64)50-25-12-9-15-55(73)39(25)69/h6,18-20,23-26,28-31,56-57,60-61,72-73H,7-17,42H2,1-5H3,(H,46,67)(H,47,59)(H,48,63)(H,49,66)(H,50,64)(H,51,65)(H,52,68)(H,53,62)(H,70,71)(H4,43,44,45)/b22-6-
InChI Key YHBAYFBDFCGZTI-HCDFXORVSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C41H70N14O18
Molecular Weight 1047.10 g/mol
Exact Mass 1046.49925144 g/mol
Topological Polar Surface Area (TPSA) 523.00 Ų
XlogP -10.40

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Delftibactin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.75% 98.95%
CHEMBL4040 P28482 MAP kinase ERK2 99.39% 83.82%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.03% 96.09%
CHEMBL3837 P07711 Cathepsin L 97.57% 96.61%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 97.34% 93.10%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 96.65% 98.33%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.20% 94.45%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 95.72% 93.00%
CHEMBL2514 O95665 Neurotensin receptor 2 95.54% 100.00%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 95.53% 96.47%
CHEMBL3137262 O60341 LSD1/CoREST complex 95.43% 97.09%
CHEMBL2094135 Q96BI3 Gamma-secretase 95.32% 98.05%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.24% 91.11%
CHEMBL4072 P07858 Cathepsin B 94.74% 93.67%
CHEMBL221 P23219 Cyclooxygenase-1 93.82% 90.17%
CHEMBL4588 P22894 Matrix metalloproteinase 8 93.76% 94.66%
CHEMBL3359 P21462 Formyl peptide receptor 1 93.47% 93.56%
CHEMBL3060 Q9Y345 Glycine transporter 2 93.38% 99.17%
CHEMBL236 P41143 Delta opioid receptor 93.35% 99.35%
CHEMBL259 P32245 Melanocortin receptor 4 93.06% 95.38%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 91.39% 95.00%
CHEMBL220 P22303 Acetylcholinesterase 91.38% 94.45%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 90.62% 90.71%
CHEMBL5103 Q969S8 Histone deacetylase 10 90.48% 90.08%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 88.32% 96.67%
CHEMBL340 P08684 Cytochrome P450 3A4 87.87% 91.19%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 87.21% 100.00%
CHEMBL204 P00734 Thrombin 87.13% 96.01%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 86.41% 96.90%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.90% 95.89%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 85.85% 96.03%
CHEMBL237 P41145 Kappa opioid receptor 85.55% 98.10%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.28% 95.56%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 84.84% 96.00%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 84.71% 97.29%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 84.69% 96.11%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 84.68% 96.38%
CHEMBL1873 P00750 Tissue-type plasminogen activator 84.67% 93.33%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 84.65% 88.42%
CHEMBL2534 O15530 3-phosphoinositide dependent protein kinase-1 84.35% 95.36%
CHEMBL230 P35354 Cyclooxygenase-2 84.32% 89.63%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 83.77% 95.50%
CHEMBL4227 P25090 Lipoxin A4 receptor 83.50% 100.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.22% 93.03%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 83.17% 95.89%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 82.82% 96.25%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.30% 97.14%
CHEMBL5028 O14672 ADAM10 81.85% 97.50%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.31% 99.23%
CHEMBL333 P08253 Matrix metalloproteinase-2 80.51% 96.31%
CHEMBL4608 P33032 Melanocortin receptor 5 80.04% 97.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 70680459
LOTUS LTS0219565
wikiData Q105348333