Dehydroaustinol

Details

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Internal ID 05470828-f501-41c1-95b6-fc6e63c22237
Taxonomy Organoheterocyclic compounds > Furopyrans
IUPAC Name (1R,2S,5S,7S,8S,9R,12S,13S)-8-hydroxy-2,6',6',9,13-pentamethyl-6,16-dimethylidenespiro[10,14,17-trioxapentacyclo[7.6.1.17,12.01,12.02,7]heptadecane-5,5'-pyran]-2',11,15-trione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C25H28O8/c1-12-21(7)16(27)24-13(2)22(9-8-15(26)31-19(22,4)5)11-10-20(24,6)23(12)17(28)30-14(3)25(23,33-24)18(29)32-21/h8-9,14,16,27H,1-2,10-11H2,3-7H3/t14-,16-,20-,21+,22+,23+,24+,25-/m0/s1
InChI Key IQBUQLYYAHHCGX-LRSNFHFMSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C25H28O8
Molecular Weight 456.50 g/mol
Exact Mass 456.17841785 g/mol
Topological Polar Surface Area (TPSA) 108.00 Ų
XlogP 1.00

Synonyms

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(1'R,2'S,3S,7'S,8'S,9'R,12'S,13'S)-8'-hydroxy-2,2,2',9',13'-pentamethyl-6',16'-bis(methylene)-6H-spiro[pyran-3,5'-[10,14,17]trioxapentacyclo[7.6.1.1(7,12).0(1,12).0(2,7)]heptadecane]-6,11',15'-trione
CHEBI:64421
Q27133275

2D Structure

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2D Structure of Dehydroaustinol

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL325 Q13547 Histone deacetylase 1 93.73% 95.92%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.33% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.33% 95.56%
CHEMBL221 P23219 Cyclooxygenase-1 91.27% 90.17%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.72% 99.23%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.00% 89.00%
CHEMBL1937 Q92769 Histone deacetylase 2 88.96% 94.75%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.35% 100.00%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 82.80% 85.00%
CHEMBL340 P08684 Cytochrome P450 3A4 82.50% 91.19%
CHEMBL4803 P29474 Nitric-oxide synthase, endothelial 81.77% 86.00%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 81.45% 94.80%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.43% 97.14%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 81.01% 93.40%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

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PubChem 56955928
LOTUS LTS0134114
wikiData Q27133275