8H-Cyclopentacyclododecen-8-one, 13,13a-bis(acetyloxy)-3-(benzoyloxy)-1,2,3,3a,6,7,9,12,13,13a-decahydro-6-hydroxy-2,5,9,9,12-pentamethyl-, (2R,3S,3aS,4E,6R,10E,12R,13R,13aR)-

Details

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Internal ID b60bc867-fc3c-4c4f-a5e7-2e5ab889f60b
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Jatrophane and cyclojatrophane diterpenoids
IUPAC Name [(1S,2R,3aR,4R,5R,6Z,11R,12Z,13aS)-3a,4-diacetyloxy-11-hydroxy-2,5,8,8,12-pentamethyl-9-oxo-1,2,3,4,5,10,11,13a-octahydrocyclopenta[12]annulen-1-yl] benzoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C31H40O8/c1-18-13-14-30(6,7)26(35)16-25(34)19(2)15-24-27(38-29(36)23-11-9-8-10-12-23)20(3)17-31(24,39-22(5)33)28(18)37-21(4)32/h8-15,18,20,24-25,27-28,34H,16-17H2,1-7H3/b14-13-,19-15-/t18-,20-,24+,25-,27+,28-,31-/m1/s1
InChI Key OQLAYVOSMBSWSF-FOFWAKMFSA-N
Popularity 5 references in papers

Physical and Chemical Properties

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Molecular Formula C31H40O8
Molecular Weight 540.60 g/mol
Exact Mass 540.27231823 g/mol
Topological Polar Surface Area (TPSA) 116.00 Ų
XlogP 4.30

Synonyms

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81542-94-1
8H-Cyclopentacyclododecen-8-one, 13,13a-bis(acetyloxy)-3-(benzoyloxy)-1,2,3,3a,6,7,9,12,13,13a-decahydro-6-hydroxy-2,5,9,9,12-pentamethyl-, (2R,3S,3aS,4E,6R,10E,12R,13R,13aR)-

2D Structure

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2D Structure of 8H-Cyclopentacyclododecen-8-one, 13,13a-bis(acetyloxy)-3-(benzoyloxy)-1,2,3,3a,6,7,9,12,13,13a-decahydro-6-hydroxy-2,5,9,9,12-pentamethyl-, (2R,3S,3aS,4E,6R,10E,12R,13R,13aR)-

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL1293249 Q13887 Kruppel-like factor 5 96.70% 86.33%
CHEMBL2581 P07339 Cathepsin D 95.87% 98.95%
CHEMBL1951 P21397 Monoamine oxidase A 95.68% 91.49%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 94.84% 99.23%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.28% 95.56%
CHEMBL221 P23219 Cyclooxygenase-1 91.99% 90.17%
CHEMBL3524 P56524 Histone deacetylase 4 91.21% 92.97%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 90.28% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 88.21% 96.09%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 86.42% 83.00%
CHEMBL2996 Q05655 Protein kinase C delta 85.85% 97.79%
CHEMBL5028 O14672 ADAM10 85.07% 97.50%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 84.45% 93.03%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 84.35% 93.00%
CHEMBL4208 P20618 Proteasome component C5 82.57% 90.00%
CHEMBL340 P08684 Cytochrome P450 3A4 81.63% 91.19%
CHEMBL1293277 O15118 Niemann-Pick C1 protein 81.25% 81.11%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 80.27% 95.50%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 80.16% 91.07%
CHEMBL1293294 P51151 Ras-related protein Rab-9A 80.13% 87.67%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Euphorbia helioscopia

Cross-Links

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PubChem 6440690
LOTUS LTS0080039
wikiData Q105013153