Daryamide A

Details

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Internal ID 87c4a810-8a7b-4c58-a264-766c1532cacd
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbonyl compounds > Cyclic ketones > Cyclohexenones
IUPAC Name (2E,4E)-N-[(3S,4R)-3-(3-amino-3-oxopropyl)-3,4-dihydroxy-6-oxocyclohexen-1-yl]-7-methylocta-2,4-dienamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C18H26N2O5/c1-12(2)6-4-3-5-7-17(24)20-13-11-18(25,9-8-16(19)23)15(22)10-14(13)21/h3-5,7,11-12,15,22,25H,6,8-10H2,1-2H3,(H2,19,23)(H,20,24)/b4-3+,7-5+/t15-,18+/m1/s1
InChI Key VLZVGRPEASVNDM-HMBRAYOKSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C18H26N2O5
Molecular Weight 350.40 g/mol
Exact Mass 350.18417193 g/mol
Topological Polar Surface Area (TPSA) 130.00 Ų
XlogP -0.10

Synonyms

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(2E,4E)-N-[(3S,4R)-3-(3-amino-3-oxopropyl)-3,4-dihydroxy-6-oxocyclohexen-1-yl]-7-methylocta-2,4-dienamide
(2E,4E)-N-((3S,4R)-3-(3-amino-3-oxopropyl)-3,4-dihydroxy-6-oxocyclohexen-1-yl)-7-methylocta-2,4-dienamide
RefChem:130974
918785-41-8
CHEMBL450849
SCHEMBL29885996
CHEBI:207289

2D Structure

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2D Structure of Daryamide A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.69% 91.11%
CHEMBL221 P23219 Cyclooxygenase-1 97.60% 90.17%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.36% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.27% 94.45%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 94.58% 89.34%
CHEMBL2581 P07339 Cathepsin D 89.71% 98.95%
CHEMBL299 P17252 Protein kinase C alpha 88.74% 98.03%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.52% 95.56%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.89% 95.89%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 86.29% 91.07%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.58% 90.71%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.70% 97.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.02% 89.00%
CHEMBL4208 P20618 Proteasome component C5 83.03% 90.00%
CHEMBL340 P08684 Cytochrome P450 3A4 82.97% 91.19%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 81.94% 94.33%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.67% 96.47%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 16099480
LOTUS LTS0033419
wikiData Q77484237