Danshenol B

Details

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Internal ID aadc21f3-8a11-46ad-a204-54330c5fa1e1
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Tanshinones, isotanshinones, and derivatives
IUPAC Name (1R,10S)-10-hydroxy-1,6,6-trimethyl-10-(2-oxopropyl)-2,7,8,9-tetrahydro-1H-naphtho[1,2-g][1]benzofuran-11-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H26O4/c1-12-11-26-19-15-7-8-16-14(6-5-9-21(16,3)4)18(15)22(25,10-13(2)23)20(24)17(12)19/h7-8,12,25H,5-6,9-11H2,1-4H3/t12-,22-/m0/s1
InChI Key KZLPKGGMSDHTRS-YTEVENLXSA-N
Popularity 6 references in papers

Physical and Chemical Properties

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Molecular Formula C22H26O4
Molecular Weight 354.40 g/mol
Exact Mass 354.18310931 g/mol
Topological Polar Surface Area (TPSA) 63.60 Ų
XlogP 3.70

Synonyms

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189308-09-6
DTXSID80172335
RefChem:919629
DTXCID9094826
(1R,10S)-10-hydroxy-1,6,6-trimethyl-10-(2-oxopropyl)-2,7,8,9-tetrahydro-1H-naphtho[1,2-g][1]benzofuran-11-one
CHEMBL2261307
Phenanthro(1,2-b)furan-11(2H)-one, 1,6,7,8,9,10-hexahydro-10-hydroxy-1,6,6-trimethyl-10-(2-oxopropyl)-, (1R,10S)-
Phenanthro(1,2-b)furan-11(2H)-one, 1,6,7,8,9,10-hexahydro-10-hydroxy-1,6,6-trimethyl-10-(2-oxopropyl)-, (1R-trans)-
orb2279386
SCHEMBL30474993
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Danshenol B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.14% 91.11%
CHEMBL4040 P28482 MAP kinase ERK2 98.34% 83.82%
CHEMBL2581 P07339 Cathepsin D 96.60% 98.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.37% 97.25%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.97% 86.33%
CHEMBL1951 P21397 Monoamine oxidase A 93.26% 91.49%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.06% 95.56%
CHEMBL1994 P08235 Mineralocorticoid receptor 91.26% 100.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.84% 99.23%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 84.52% 91.24%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 81.65% 96.09%
CHEMBL340 P08684 Cytochrome P450 3A4 81.49% 91.19%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 81.12% 92.62%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 81.09% 90.93%
CHEMBL4208 P20618 Proteasome component C5 80.93% 90.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.75% 89.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 80.60% 97.09%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Salvia miltiorrhiza

Cross-Links

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PubChem 3083515
NPASS NPC212207
ChEMBL CHEMBL2261307
LOTUS LTS0244450
wikiData Q83042437