Dankastatin B

Details

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Internal ID 1a98e193-2e15-482f-b81d-c6b8d112deff
Taxonomy Organoheterocyclic compounds > Benzopyrans
IUPAC Name (2E,4E,6R)-N-[(3S,4aS,8R,8aR)-6,8-dichloro-4a-hydroxy-7-oxo-3,4,8,8a-tetrahydro-2H-chromen-3-yl]-4,6-dimethyldodeca-2,4-dienamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C23H33Cl2NO4/c1-4-5-6-7-8-15(2)11-16(3)9-10-19(27)26-17-12-23(29)13-18(24)21(28)20(25)22(23)30-14-17/h9-11,13,15,17,20,22,29H,4-8,12,14H2,1-3H3,(H,26,27)/b10-9+,16-11+/t15-,17+,20+,22+,23+/m1/s1
InChI Key FOYHOCBUHQKEDQ-HUWMOLIRSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C23H33Cl2NO4
Molecular Weight 458.40 g/mol
Exact Mass 457.1786639 g/mol
Topological Polar Surface Area (TPSA) 75.60 Ų
XlogP 5.80

Synonyms

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CHEMBL256282
(2E,4E,6R)-N-[(3S,4aS,8R,8aR)-6,8-dichloro-4a-hydroxy-7-oxo-3,4,8,8a-tetrahydro-2H-chromen-3-yl]-4,6-dimethyldodeca-2,4-dienamide

2D Structure

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2D Structure of Dankastatin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.51% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.08% 94.45%
CHEMBL221 P23219 Cyclooxygenase-1 95.89% 90.17%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.52% 96.09%
CHEMBL3060 Q9Y345 Glycine transporter 2 92.75% 99.17%
CHEMBL2581 P07339 Cathepsin D 91.53% 98.95%
CHEMBL3359 P21462 Formyl peptide receptor 1 90.75% 93.56%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.61% 90.71%
CHEMBL340 P08684 Cytochrome P450 3A4 87.39% 91.19%
CHEMBL4227 P25090 Lipoxin A4 receptor 87.30% 100.00%
CHEMBL218 P21554 Cannabinoid CB1 receptor 87.10% 96.61%
CHEMBL299 P17252 Protein kinase C alpha 86.15% 98.03%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 85.96% 95.00%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 85.61% 96.90%
CHEMBL3401 O75469 Pregnane X receptor 84.83% 94.73%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 82.92% 95.50%
CHEMBL2514 O95665 Neurotensin receptor 2 81.95% 100.00%
CHEMBL5255 O00206 Toll-like receptor 4 81.70% 92.50%
CHEMBL230 P35354 Cyclooxygenase-2 81.63% 89.63%
CHEMBL253 P34972 Cannabinoid CB2 receptor 81.22% 97.25%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.77% 89.00%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 80.26% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 24854522
LOTUS LTS0106745
wikiData Q75062567