(D-Leu1)MC-M(O2)R

Details

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Internal ID 6d81fe2e-32c0-4b9c-8220-ec2e92b5bf7e
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name (5R,8S,11R,12S,15S,18S,19S,22R)-15-[3-(diaminomethylideneamino)propyl]-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,12,19-trimethyl-2-methylidene-5-(2-methylpropyl)-8-(2-methylsulfonylethyl)-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptazacyclopentacosane-11,22-dicarboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C51H78N10O14S/c1-28(2)25-39-48(68)57-37(22-24-76(10,73)74)47(67)60-42(50(71)72)32(6)44(64)56-36(17-14-23-54-51(52)53)46(66)55-35(19-18-29(3)26-30(4)40(75-9)27-34-15-12-11-13-16-34)31(5)43(63)58-38(49(69)70)20-21-41(62)61(8)33(7)45(65)59-39/h11-13,15-16,18-19,26,28,30-32,35-40,42H,7,14,17,20-25,27H2,1-6,8-10H3,(H,55,66)(H,56,64)(H,57,68)(H,58,63)(H,59,65)(H,60,67)(H,69,70)(H,71,72)(H4,52,53,54)/b19-18+,29-26+/t30-,31-,32-,35-,36-,37-,38+,39+,40-,42+/m0/s1
InChI Key PSBIEJGKICVXRC-OIGYFXLDSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C51H78N10O14S
Molecular Weight 1087.30 g/mol
Exact Mass 1086.54196837 g/mol
Topological Polar Surface Area (TPSA) 386.00 Ų
XlogP 1.70

Synonyms

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DTXSID901047597

2D Structure

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2D Structure of (D-Leu1)MC-M(O2)R

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4040 P28482 MAP kinase ERK2 100.00% 83.82%
CHEMBL2581 P07339 Cathepsin D 99.79% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.57% 96.09%
CHEMBL3837 P07711 Cathepsin L 98.17% 96.61%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 98.00% 95.56%
CHEMBL4072 P07858 Cathepsin B 96.34% 93.67%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.96% 86.33%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.05% 94.45%
CHEMBL5608 Q16288 NT-3 growth factor receptor 91.20% 95.89%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 90.60% 91.11%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 88.09% 91.71%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 88.00% 95.89%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.95% 90.71%
CHEMBL3060 Q9Y345 Glycine transporter 2 87.09% 99.17%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.60% 97.09%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 85.62% 96.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.20% 97.14%
CHEMBL226 P30542 Adenosine A1 receptor 84.05% 95.93%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 84.05% 97.64%
CHEMBL1255126 O15151 Protein Mdm4 82.69% 90.20%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.69% 93.00%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 81.93% 100.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.60% 89.00%
CHEMBL4588 P22894 Matrix metalloproteinase 8 81.29% 94.66%
CHEMBL4644 P41968 Melanocortin receptor 3 80.44% 99.52%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 80.40% 97.33%
CHEMBL5103 Q969S8 Histone deacetylase 10 80.20% 90.08%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 155802273
LOTUS LTS0088631
wikiData Q104246726