(D-Asp3)MC-LW

Details

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Internal ID 3ea6ebbe-d94b-49af-9156-bd5c091870e2
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name (5R,8S,11R,15S,18S,19S,22R)-15-(1H-indol-3-ylmethyl)-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,5,19-trimethyl-2-methylidene-8-(2-methylpropyl)-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptazacyclopentacosane-11,22-dicarboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C53H70N8O12/c1-29(2)23-41-50(67)60-43(53(71)72)27-45(62)56-42(26-36-28-54-39-18-14-13-17-37(36)39)51(68)57-38(20-19-30(3)24-31(4)44(73-9)25-35-15-11-10-12-16-35)32(5)47(64)58-40(52(69)70)21-22-46(63)61(8)34(7)49(66)55-33(6)48(65)59-41/h10-20,24,28-29,31-33,38,40-44,54H,7,21-23,25-27H2,1-6,8-9H3,(H,55,66)(H,56,62)(H,57,68)(H,58,64)(H,59,65)(H,60,67)(H,69,70)(H,71,72)/b20-19+,30-24+/t31-,32-,33+,38-,40+,41-,42-,43+,44-/m0/s1
InChI Key KEUIEPSPMZCRNU-MGDFNBQSSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C53H70N8O12
Molecular Weight 1011.20 g/mol
Exact Mass 1010.51131970 g/mol
Topological Polar Surface Area (TPSA) 295.00 Ų
XlogP 4.60

Synonyms

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DTXSID601335648

2D Structure

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2D Structure of (D-Asp3)MC-LW

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4040 P28482 MAP kinase ERK2 99.97% 83.82%
CHEMBL2581 P07339 Cathepsin D 99.91% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.59% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 97.42% 95.56%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 97.18% 97.64%
CHEMBL1951 P21397 Monoamine oxidase A 97.00% 91.49%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.97% 91.11%
CHEMBL5103 Q969S8 Histone deacetylase 10 96.54% 90.08%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 96.42% 91.71%
CHEMBL3837 P07711 Cathepsin L 96.29% 96.61%
CHEMBL1937 Q92769 Histone deacetylase 2 95.79% 94.75%
CHEMBL3310 Q96DB2 Histone deacetylase 11 95.39% 88.56%
CHEMBL3192 Q9BY41 Histone deacetylase 8 94.91% 93.99%
CHEMBL4072 P07858 Cathepsin B 91.84% 93.67%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.71% 85.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.55% 86.33%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 89.07% 94.45%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.78% 89.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.71% 95.89%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.23% 99.23%
CHEMBL4644 P41968 Melanocortin receptor 3 87.78% 99.52%
CHEMBL1255126 O15151 Protein Mdm4 87.71% 90.20%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 87.27% 96.39%
CHEMBL2535 P11166 Glucose transporter 86.17% 98.75%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.80% 99.17%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.18% 97.09%
CHEMBL217 P14416 Dopamine D2 receptor 82.33% 95.62%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 81.89% 90.71%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 81.88% 95.50%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 81.01% 92.67%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 155802154
LOTUS LTS0048871
wikiData Q104246620