(D-Asp3,Dha7)MC-E(OMe)E(OMe)

Details

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Internal ID e724b36f-e597-4098-a096-875b4031215c
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name (5R,8S,11R,15S,18S,19S,22R)-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-8,15-bis(3-methoxy-3-oxopropyl)-5,19-dimethyl-2-methylidene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptazacyclopentacosane-11,22-dicarboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C47H65N7O16/c1-25(22-26(2)36(68-6)23-30-12-10-9-11-13-30)14-15-31-27(3)41(59)53-34(46(64)65)16-19-37(55)48-28(4)42(60)49-29(5)43(61)52-33(18-21-40(58)70-8)45(63)54-35(47(66)67)24-38(56)50-32(44(62)51-31)17-20-39(57)69-7/h9-15,22,26-27,29,31-36H,4,16-21,23-24H2,1-3,5-8H3,(H,48,55)(H,49,60)(H,50,56)(H,51,62)(H,52,61)(H,53,59)(H,54,63)(H,64,65)(H,66,67)/b15-14+,25-22+/t26-,27-,29+,31-,32-,33-,34+,35+,36-/m0/s1
InChI Key HWVHMIUFTWETCB-NPBCHJBDSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C47H65N7O16
Molecular Weight 984.10 g/mol
Exact Mass 983.44877901 g/mol
Topological Polar Surface Area (TPSA) 340.00 Ų
XlogP 1.10

Synonyms

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DTXSID701335310

2D Structure

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2D Structure of (D-Asp3,Dha7)MC-E(OMe)E(OMe)

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.60% 98.95%
CHEMBL4040 P28482 MAP kinase ERK2 99.59% 83.82%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.83% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.72% 85.14%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.75% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.05% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.95% 95.56%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 93.77% 97.64%
CHEMBL221 P23219 Cyclooxygenase-1 92.11% 90.17%
CHEMBL3060 Q9Y345 Glycine transporter 2 90.31% 99.17%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.06% 95.89%
CHEMBL5103 Q969S8 Histone deacetylase 10 89.70% 90.08%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 89.70% 95.50%
CHEMBL1293249 Q13887 Kruppel-like factor 5 87.23% 86.33%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 86.96% 91.07%
CHEMBL1937 Q92769 Histone deacetylase 2 86.65% 94.75%
CHEMBL340 P08684 Cytochrome P450 3A4 86.51% 91.19%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 86.06% 97.14%
CHEMBL1255126 O15151 Protein Mdm4 85.43% 90.20%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.92% 99.23%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 83.81% 82.69%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 83.78% 95.89%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.06% 93.03%
CHEMBL2327 P21452 Neurokinin 2 receptor 82.76% 98.89%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 81.32% 91.71%
CHEMBL4227 P25090 Lipoxin A4 receptor 80.77% 100.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.66% 90.71%
CHEMBL3137262 O60341 LSD1/CoREST complex 80.57% 97.09%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.48% 96.47%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146683844
LOTUS LTS0130977
wikiData Q105110600