Cytochalasin Z20

Details

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Internal ID 80857656-ddb7-4afd-8bf6-52aa6e580d5c
Taxonomy Organoheterocyclic compounds > Isoindoles and derivatives > Isoindolines > Isoindolones
IUPAC Name (1aS,2S,2aS,5S,5aS,6S,6aR)-5-benzyl-2a-hydroxy-2-[(E,4S,6S)-6-hydroxy-4-methyl-5-oxohept-1-enyl]-6,6a-dimethyl-1a,2,4,5,5a,6-hexahydrooxireno[2,3-f]isoindol-3-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C25H33NO5/c1-14(21(28)16(3)27)9-8-12-18-22-24(4,31-22)15(2)20-19(26-23(29)25(18,20)30)13-17-10-6-5-7-11-17/h5-8,10-12,14-16,18-20,22,27,30H,9,13H2,1-4H3,(H,26,29)/b12-8+/t14-,15-,16-,18-,19-,20-,22-,24+,25+/m0/s1
InChI Key NBVORADFJOAZAV-HFUIFYSESA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C25H33NO5
Molecular Weight 427.50 g/mol
Exact Mass 427.23587315 g/mol
Topological Polar Surface Area (TPSA) 99.20 Ų
XlogP 2.30

Synonyms

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CHEMBL4793268

2D Structure

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2D Structure of Cytochalasin Z20

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.99% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.14% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.33% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.38% 95.56%
CHEMBL4040 P28482 MAP kinase ERK2 93.52% 83.82%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.40% 91.11%
CHEMBL221 P23219 Cyclooxygenase-1 91.38% 90.17%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 84.30% 96.47%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.25% 94.45%
CHEMBL1293249 Q13887 Kruppel-like factor 5 84.09% 86.33%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.24% 89.00%
CHEMBL3401 O75469 Pregnane X receptor 83.14% 94.73%
CHEMBL255 P29275 Adenosine A2b receptor 82.96% 98.59%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 81.93% 95.50%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 80.22% 94.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139586873
LOTUS LTS0063829
wikiData Q77516521