Cytochalasin U

Details

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Internal ID bd863110-98d6-42b9-9e09-25ad0ec071b8
Taxonomy Alkaloids and derivatives > Cytochalasans
IUPAC Name [(1S,2R,3E,5R,7S,9E,11S,14S,15R,16S)-16-benzyl-5-hydroxy-13-(hydroxymethyl)-5,7,14-trimethyl-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9,12-trien-2-yl] acetate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H39NO5/c1-19-9-8-12-24-16-23(18-32)20(2)27-25(15-22-10-6-5-7-11-22)31-28(34)30(24,27)26(36-21(3)33)13-14-29(4,35)17-19/h5-8,10-14,16,19-20,24-27,32,35H,9,15,17-18H2,1-4H3,(H,31,34)/b12-8+,14-13+/t19-,20+,24-,25-,26+,27-,29-,30+/m0/s1
InChI Key OCZJGPJVAQGKFA-IJOFPKGLSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C30H39NO5
Molecular Weight 493.60 g/mol
Exact Mass 493.28282334 g/mol
Topological Polar Surface Area (TPSA) 95.90 Ų
XlogP 3.30

Synonyms

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CHEMBL5198126

2D Structure

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2D Structure of Cytochalasin U

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.61% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.55% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.55% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.31% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.58% 85.14%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 93.86% 94.62%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.73% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.51% 86.33%
CHEMBL253 P34972 Cannabinoid CB2 receptor 87.71% 97.25%
CHEMBL216 P11229 Muscarinic acetylcholine receptor M1 86.77% 94.23%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 86.35% 82.69%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.08% 99.23%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.16% 97.09%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 83.23% 95.50%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 82.38% 94.08%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.03% 95.89%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 80.36% 97.64%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

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PubChem 139588903
LOTUS LTS0080926
wikiData Q105189662