Cyclo(L-alpha-Glutamyl-L-prolyl-L-alpha-

Details

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Internal ID ca8adfc5-f002-427e-9c2f-1122900da02f
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Cyclic peptides
IUPAC Name 3-[(3S,6S,12S,15S)-12-(2-carboxyethyl)-2,5,11,14-tetraoxo-1,4,10,13-tetrazatricyclo[13.3.0.06,10]octadecan-3-yl]propanoic acid
SMILES (Canonical) C1CC2C(=O)NC(C(=O)N3CCCC3C(=O)NC(C(=O)N2C1)CCC(=O)O)CCC(=O)O
SMILES (Isomeric) C1C[C@H]2C(=O)N[C@H](C(=O)N3CCC[C@H]3C(=O)N[C@H](C(=O)N2C1)CCC(=O)O)CCC(=O)O
InChI InChI=1S/C20H28N4O8/c25-15(26)7-5-11-19(31)23-9-1-3-13(23)17(29)21-12(6-8-16(27)28)20(32)24-10-2-4-14(24)18(30)22-11/h11-14H,1-10H2,(H,21,29)(H,22,30)(H,25,26)(H,27,28)/t11-,12-,13-,14-/m0/s1
InChI Key BOVBRDXZRVJXLF-XUXIUFHCSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C20H28N4O8
Molecular Weight 452.50 g/mol
Exact Mass 452.19071386 g/mol
Topological Polar Surface Area (TPSA) 173.00 Ų
XlogP -1.40

Synonyms

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Cyclo(L-alpha-Glutamyl-L-prolyl-L-alpha-

2D Structure

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2D Structure of Cyclo(L-alpha-Glutamyl-L-prolyl-L-alpha-

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 97.52% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.13% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.00% 85.14%
CHEMBL1902 P62942 FK506-binding protein 1A 94.11% 97.05%
CHEMBL217 P14416 Dopamine D2 receptor 91.29% 95.62%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 86.89% 93.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 86.84% 93.03%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.32% 97.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 85.53% 97.25%
CHEMBL5103 Q969S8 Histone deacetylase 10 85.00% 90.08%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 84.87% 82.38%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 84.74% 97.64%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.28% 94.45%
CHEMBL228 P31645 Serotonin transporter 83.34% 95.51%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.31% 95.89%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 83.20% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 82.61% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.53% 99.23%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 81.17% 93.04%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 44584282
LOTUS LTS0012609
wikiData Q77280403