3,9-Dibenzyl-25-ethyl-6-(1-hydroxyethyl)-4,7,10,15,20,23-hexamethyl-12-propan-2-yl-1-oxa-4,7,10,13,20-pentazacyclopentacos-18-ene-2,5,8,11,14,21-hexone

Details

Top
Internal ID d51cb553-be73-40ca-a07e-a90d0c70f1f7
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name 3,9-dibenzyl-25-ethyl-6-(1-hydroxyethyl)-4,7,10,15,20,23-hexamethyl-12-propan-2-yl-1-oxa-4,7,10,13,20-pentazacyclopentacos-18-ene-2,5,8,11,14,21-hexone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C46H67N5O8/c1-11-36-26-31(4)27-39(53)48(7)25-19-18-20-32(5)42(54)47-40(30(2)3)44(56)49(8)37(28-34-21-14-12-15-22-34)43(55)51(10)41(33(6)52)45(57)50(9)38(46(58)59-36)29-35-23-16-13-17-24-35/h12-17,19,21-25,30-33,36-38,40-41,52H,11,18,20,26-29H2,1-10H3,(H,47,54)
InChI Key LJNGIVUAMWQJIA-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

Top
Molecular Formula C46H67N5O8
Molecular Weight 818.10 g/mol
Exact Mass 817.49896411 g/mol
Topological Polar Surface Area (TPSA) 157.00 Ų
XlogP 6.60

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of 3,9-Dibenzyl-25-ethyl-6-(1-hydroxyethyl)-4,7,10,15,20,23-hexamethyl-12-propan-2-yl-1-oxa-4,7,10,13,20-pentazacyclopentacos-18-ene-2,5,8,11,14,21-hexone

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.63% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 99.03% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.33% 96.09%
CHEMBL4072 P07858 Cathepsin B 97.11% 93.67%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.77% 95.56%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.00% 94.45%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 91.87% 97.64%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.69% 97.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.41% 91.11%
CHEMBL4208 P20618 Proteasome component C5 90.27% 90.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 88.54% 90.08%
CHEMBL3004 P33527 Multidrug resistance-associated protein 1 88.51% 96.37%
CHEMBL221 P23219 Cyclooxygenase-1 87.61% 90.17%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 87.14% 93.03%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.80% 86.33%
CHEMBL253 P34972 Cannabinoid CB2 receptor 85.67% 97.25%
CHEMBL1949 P62937 Cyclophilin A 85.47% 98.57%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.17% 99.23%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 83.21% 93.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.53% 95.89%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 81.50% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.24% 89.00%
CHEMBL255 P29275 Adenosine A2b receptor 81.05% 98.59%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 80.41% 97.14%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.02% 96.47%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 162864995
LOTUS LTS0224050
wikiData Q104171008