(3R,6S,9R,12S,15R,18R)-12-benzyl-6-(hydroxymethyl)-3-(1H-indol-3-ylmethyl)-18-methyl-9,15-di(propan-2-yl)-1,4,7,10,13,16,19-heptazacyclotricosane-2,5,8,11,14,17,20-heptone

Details

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Internal ID d11fa1a5-2764-4dfd-a3ef-d668be800e3f
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name (3R,6S,9R,12S,15R,18R)-12-benzyl-6-(hydroxymethyl)-3-(1H-indol-3-ylmethyl)-18-methyl-9,15-di(propan-2-yl)-1,4,7,10,13,16,19-heptazacyclotricosane-2,5,8,11,14,17,20-heptone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C40H54N8O8/c1-22(2)33-39(55)45-29(18-25-12-7-6-8-13-25)37(53)48-34(23(3)4)40(56)46-31(21-49)38(54)44-30(19-26-20-42-28-15-10-9-14-27(26)28)36(52)41-17-11-16-32(50)43-24(5)35(51)47-33/h6-10,12-15,20,22-24,29-31,33-34,42,49H,11,16-19,21H2,1-5H3,(H,41,52)(H,43,50)(H,44,54)(H,45,55)(H,46,56)(H,47,51)(H,48,53)/t24-,29+,30-,31+,33-,34-/m1/s1
InChI Key DYUXTXRHHWGWDU-RNCACNLSSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C40H54N8O8
Molecular Weight 774.90 g/mol
Exact Mass 774.40646071 g/mol
Topological Polar Surface Area (TPSA) 240.00 Ų
XlogP 2.80

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of (3R,6S,9R,12S,15R,18R)-12-benzyl-6-(hydroxymethyl)-3-(1H-indol-3-ylmethyl)-18-methyl-9,15-di(propan-2-yl)-1,4,7,10,13,16,19-heptazacyclotricosane-2,5,8,11,14,17,20-heptone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.49% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.95% 91.11%
CHEMBL4040 P28482 MAP kinase ERK2 98.09% 83.82%
CHEMBL5103 Q969S8 Histone deacetylase 10 96.96% 90.08%
CHEMBL3310 Q96DB2 Histone deacetylase 11 96.27% 88.56%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 95.66% 97.64%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.37% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.34% 95.56%
CHEMBL1937 Q92769 Histone deacetylase 2 92.95% 94.75%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.55% 97.09%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 91.76% 91.71%
CHEMBL1949 P62937 Cyclophilin A 90.64% 98.57%
CHEMBL3192 Q9BY41 Histone deacetylase 8 90.63% 93.99%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 89.31% 85.14%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 89.28% 92.62%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 87.98% 90.71%
CHEMBL213 P08588 Beta-1 adrenergic receptor 85.97% 95.56%
CHEMBL2996 Q05655 Protein kinase C delta 85.20% 97.79%
CHEMBL253 P34972 Cannabinoid CB2 receptor 85.14% 97.25%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 85.07% 95.50%
CHEMBL5896 O75164 Lysine-specific demethylase 4A 83.83% 99.09%
CHEMBL1951 P21397 Monoamine oxidase A 83.80% 91.49%
CHEMBL226 P30542 Adenosine A1 receptor 83.30% 95.93%
CHEMBL1914 P06276 Butyrylcholinesterase 82.71% 95.00%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 82.37% 92.67%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 82.25% 94.45%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.01% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.79% 89.00%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 81.06% 95.83%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 636495
LOTUS LTS0027004
wikiData Q105260630