Cycloaspeptide F

Details

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Internal ID a88559ee-e7bb-4d4e-95b2-12b4c8eb910c
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Oligopeptides
IUPAC Name (4S,7S,10S,13S)-10-benzyl-5,11,13-trimethyl-7-(2-methylpropyl)-4-[[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl]-2,5,8,11,14-pentazabicyclo[14.4.0]icosa-1(20),16,18-triene-3,6,9,12,15-pentone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C42H53N5O11/c1-23(2)19-30-41(56)47(5)32(21-26-15-17-27(18-16-26)57-42-36(51)35(50)34(49)33(22-48)58-42)38(53)44-29-14-10-9-13-28(29)37(52)43-24(3)40(55)46(4)31(39(54)45-30)20-25-11-7-6-8-12-25/h6-18,23-24,30-36,42,48-51H,19-22H2,1-5H3,(H,43,52)(H,44,53)(H,45,54)/t24-,30-,31-,32-,33+,34+,35-,36+,42+/m0/s1
InChI Key HGCDDJBOTFSYBL-HEZYXVPISA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C42H53N5O11
Molecular Weight 803.90 g/mol
Exact Mass 803.37415752 g/mol
Topological Polar Surface Area (TPSA) 227.00 Ų
XlogP 2.50

Synonyms

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DTXSID001017573
1174132-23-0
(4S,7S,10S,13S)-10-benzyl-5,11,13-trimethyl-7-(2-methylpropyl)-4-((4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyphenyl)methyl)-2,5,8,11,14-pentazabicyclo(14.4.0)icosa-1(20),16,18-triene-3,6,9,12,15-pentone
(4S,7S,10S,13S)-10-benzyl-5,11,13-trimethyl-7-(2-methylpropyl)-4-[[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl]-2,5,8,11,14-pentazabicyclo[14.4.0]icosa-1(20),16,18-triene-3,6,9,12,15-pentone
RefChem:129373
DTXCID401475757
(4S,7S,10S,13S)-7-benzyl-4,6,12-trimethyl-10-(2-methylpropyl)-13-((4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyphenyl)methyl)-3,6,9,12,15-pentazabicyclo(14.4.0)icosa-1(20),16,18-triene-2,5,8,11,14-pentone
CHEMBL553621
CHEBI:198160
4-{[(3S,6S,9S,12S)-9-Benzyl-4,10,12-trimethyl-6-(2-methylpropyl)-2,5,8,11,14-pentaoxo-1,2,3,4,5,6,7,8,9,10,11,12,13,14-tetradecahydro-1,4,7,10,13-benzopentaazacyclohexadecin-3-yl]methyl}phenyl beta-D-glucopyranoside

2D Structure

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2D Structure of Cycloaspeptide F

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.88% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.95% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.90% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.96% 95.56%
CHEMBL253 P34972 Cannabinoid CB2 receptor 94.93% 97.25%
CHEMBL226 P30542 Adenosine A1 receptor 93.94% 95.93%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 93.00% 95.50%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.14% 85.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.52% 86.33%
CHEMBL333 P08253 Matrix metalloproteinase-2 90.91% 96.31%
CHEMBL221 P23219 Cyclooxygenase-1 90.23% 90.17%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 90.13% 89.67%
CHEMBL218 P21554 Cannabinoid CB1 receptor 89.56% 96.61%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 88.70% 94.00%
CHEMBL4072 P07858 Cathepsin B 88.63% 93.67%
CHEMBL4208 P20618 Proteasome component C5 88.32% 90.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 87.76% 90.08%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 86.37% 99.15%
CHEMBL3060 Q9Y345 Glycine transporter 2 86.15% 99.17%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 85.58% 94.62%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 84.56% 93.00%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 84.11% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.06% 97.09%
CHEMBL1949 P62937 Cyclophilin A 83.84% 98.57%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.66% 89.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.63% 95.89%
CHEMBL1937 Q92769 Histone deacetylase 2 81.56% 94.75%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 81.46% 96.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 44234959
LOTUS LTS0070585
wikiData Q75058529