Cyclo-Tryprostatin D

Details

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Internal ID d3b53d5c-3b62-464c-b259-5feda4c01fe5
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Pyridoindoles > Beta carbolines
IUPAC Name (1R,12S,15S)-1-hydroxy-12-(2-methylprop-1-enyl)-10,13,19-triazapentacyclo[11.7.0.03,11.04,9.015,19]icosa-3(11),4,6,8-tetraene-2,14,20-trione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H21N3O4/c1-11(2)10-15-17-16(12-6-3-4-7-13(12)22-17)18(25)21(28)20(27)23-9-5-8-14(23)19(26)24(15)21/h3-4,6-7,10,14-15,22,28H,5,8-9H2,1-2H3/t14-,15-,21+/m0/s1
InChI Key PRHXKXPDGLCPPT-VFCRVFHLSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C21H21N3O4
Molecular Weight 379.40 g/mol
Exact Mass 379.15320616 g/mol
Topological Polar Surface Area (TPSA) 93.70 Ų
XlogP 2.00

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Cyclo-Tryprostatin D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.24% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.65% 91.11%
CHEMBL1902 P62942 FK506-binding protein 1A 97.27% 97.05%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 97.01% 95.56%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.91% 94.45%
CHEMBL240 Q12809 HERG 93.95% 89.76%
CHEMBL1806 P11388 DNA topoisomerase II alpha 93.28% 89.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.01% 96.09%
CHEMBL5103 Q969S8 Histone deacetylase 10 92.71% 90.08%
CHEMBL3524 P56524 Histone deacetylase 4 91.40% 92.97%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.00% 99.23%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 89.87% 85.14%
CHEMBL3310 Q96DB2 Histone deacetylase 11 89.19% 88.56%
CHEMBL1937 Q92769 Histone deacetylase 2 88.40% 94.75%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 87.82% 82.69%
CHEMBL284 P27487 Dipeptidyl peptidase IV 87.74% 95.69%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.71% 95.89%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 87.47% 93.03%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.46% 97.09%
CHEMBL217 P14416 Dopamine D2 receptor 81.79% 95.62%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 81.21% 97.64%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 80.81% 97.50%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 80.62% 93.04%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10547736
LOTUS LTS0094462
wikiData Q77515148