Cyanopeptolin CP1049

Details

Top
Internal ID c8980eaa-05b4-4f34-b728-987baceabfcc
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name 4-[[15-(5-amino-5-iminopentyl)-2-benzyl-21-hydroxy-5-[2-(4-hydroxyphenyl)ethyl]-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-8-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(octanoylamino)-4-oxobutanoic acid
SMILES (Canonical) CCCCCCCC(=O)NC(CC(=O)O)C(=O)NC1C(OC(=O)C(NC(=O)C(N(C(=O)C(N2C(CCC(C2=O)NC(=O)C(NC1=O)CCCCC(=N)N)O)CC3=CC=CC=C3)C)CCC4=CC=C(C=C4)O)C(C)C)C
SMILES (Isomeric) CCCCCCCC(=O)NC(CC(=O)O)C(=O)NC1C(OC(=O)C(NC(=O)C(N(C(=O)C(N2C(CCC(C2=O)NC(=O)C(NC1=O)CCCCC(=N)N)O)CC3=CC=CC=C3)C)CCC4=CC=C(C=C4)O)C(C)C)C
InChI InChI=1S/C53H77N9O13/c1-6-7-8-9-13-20-42(64)56-38(30-44(66)67)48(69)60-46-32(4)75-53(74)45(31(2)3)59-49(70)39(27-23-33-21-24-35(63)25-22-33)61(5)52(73)40(29-34-16-11-10-12-17-34)62-43(65)28-26-37(51(62)72)58-47(68)36(57-50(46)71)18-14-15-19-41(54)55/h10-12,16-17,21-22,24-25,31-32,36-40,43,45-46,63,65H,6-9,13-15,18-20,23,26-30H2,1-5H3,(H3,54,55)(H,56,64)(H,57,71)(H,58,68)(H,59,70)(H,60,69)(H,66,67)
InChI Key XTMLAEGIWFDMIU-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

Top
Molecular Formula C53H77N9O13
Molecular Weight 1048.20 g/mol
Exact Mass 1047.56408354 g/mol
Topological Polar Surface Area (TPSA) 340.00 Ų
XlogP 4.10

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of Cyanopeptolin CP1049

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.96% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.29% 96.09%
CHEMBL3060 Q9Y345 Glycine transporter 2 99.22% 99.17%
CHEMBL4040 P28482 MAP kinase ERK2 98.27% 83.82%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.93% 91.11%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 96.78% 92.08%
CHEMBL221 P23219 Cyclooxygenase-1 96.44% 90.17%
CHEMBL5103 Q969S8 Histone deacetylase 10 93.76% 90.08%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.61% 95.56%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.59% 94.45%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 93.59% 95.89%
CHEMBL4072 P07858 Cathepsin B 92.84% 93.67%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 92.76% 97.64%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 92.18% 95.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.98% 86.33%
CHEMBL236 P41143 Delta opioid receptor 91.07% 99.35%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 91.00% 93.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 90.56% 97.14%
CHEMBL3891 P07384 Calpain 1 90.46% 93.04%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.00% 97.09%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.18% 99.23%
CHEMBL3359 P21462 Formyl peptide receptor 1 89.10% 93.56%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 88.71% 90.71%
CHEMBL1949 P62937 Cyclophilin A 88.57% 98.57%
CHEMBL4462 Q8IXJ6 NAD-dependent deacetylase sirtuin 2 88.56% 90.24%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.18% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.95% 89.00%
CHEMBL3776 Q14790 Caspase-8 87.59% 97.06%
CHEMBL226 P30542 Adenosine A1 receptor 87.56% 95.93%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 87.43% 100.00%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 85.18% 100.00%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 83.95% 96.47%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 83.62% 97.33%
CHEMBL3837 P07711 Cathepsin L 83.51% 96.61%
CHEMBL2514 O95665 Neurotensin receptor 2 82.93% 100.00%
CHEMBL340 P08684 Cytochrome P450 3A4 82.30% 91.19%
CHEMBL4101 P17612 cAMP-dependent protein kinase alpha-catalytic subunit 81.71% 82.86%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 81.49% 90.93%
CHEMBL5805 Q9NR97 Toll-like receptor 8 81.43% 96.25%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 80.90% 82.38%
CHEMBL3468 P55210 Caspase-7 80.88% 95.68%
CHEMBL2996 Q05655 Protein kinase C delta 80.36% 97.79%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 146682043
LOTUS LTS0079601
wikiData Q105341665