Cyanopeptolin CP1048

Details

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Internal ID d9dd8534-ccdf-4c8c-b16e-bde520fe7854
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name 4-[[2-benzyl-15-[3-(diaminomethylideneamino)propyl]-21-hydroxy-5-[2-(4-hydroxyphenyl)ethyl]-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-8-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(octanoylamino)-4-oxobutanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C52H76N10O13/c1-6-7-8-9-13-18-40(64)56-37(29-42(66)67)46(69)60-44-31(4)75-51(74)43(30(2)3)59-47(70)38(25-21-32-19-22-34(63)23-20-32)61(5)50(73)39(28-33-15-11-10-12-16-33)62-41(65)26-24-36(49(62)72)58-45(68)35(57-48(44)71)17-14-27-55-52(53)54/h10-12,15-16,19-20,22-23,30-31,35-39,41,43-44,63,65H,6-9,13-14,17-18,21,24-29H2,1-5H3,(H,56,64)(H,57,71)(H,58,68)(H,59,70)(H,60,69)(H,66,67)(H4,53,54,55)
InChI Key VYXPXPDSGOMRCH-UHFFFAOYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C52H76N10O13
Molecular Weight 1049.20 g/mol
Exact Mass 1048.55933252 g/mol
Topological Polar Surface Area (TPSA) 355.00 Ų
XlogP 3.20

Synonyms

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DTXSID501047945

2D Structure

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2D Structure of Cyanopeptolin CP1048

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.97% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.45% 96.09%
CHEMBL3060 Q9Y345 Glycine transporter 2 99.38% 99.17%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.21% 91.11%
CHEMBL4040 P28482 MAP kinase ERK2 98.05% 83.82%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 97.34% 92.08%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.69% 94.45%
CHEMBL236 P41143 Delta opioid receptor 94.94% 99.35%
CHEMBL4072 P07858 Cathepsin B 94.86% 93.67%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.86% 95.56%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 93.51% 95.89%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 93.11% 97.64%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 92.80% 90.71%
CHEMBL5103 Q969S8 Histone deacetylase 10 92.37% 90.08%
CHEMBL3837 P07711 Cathepsin L 92.10% 96.61%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 91.97% 93.00%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 90.59% 95.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.53% 86.33%
CHEMBL4644 P41968 Melanocortin receptor 3 90.41% 99.52%
CHEMBL1806 P11388 DNA topoisomerase II alpha 89.55% 89.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.19% 97.09%
CHEMBL221 P23219 Cyclooxygenase-1 88.79% 90.17%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.42% 99.23%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.09% 95.89%
CHEMBL3776 Q14790 Caspase-8 87.80% 97.06%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 87.74% 97.14%
CHEMBL1949 P62937 Cyclophilin A 87.26% 98.57%
CHEMBL3891 P07384 Calpain 1 87.09% 93.04%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 87.00% 100.00%
CHEMBL226 P30542 Adenosine A1 receptor 86.78% 95.93%
CHEMBL3359 P21462 Formyl peptide receptor 1 86.67% 93.56%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 86.29% 100.00%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 84.71% 96.47%
CHEMBL2535 P11166 Glucose transporter 83.25% 98.75%
CHEMBL4588 P22894 Matrix metalloproteinase 8 83.11% 94.66%
CHEMBL4608 P33032 Melanocortin receptor 5 81.60% 97.00%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 81.42% 90.93%
CHEMBL5805 Q9NR97 Toll-like receptor 8 81.28% 96.25%
CHEMBL255 P29275 Adenosine A2b receptor 81.17% 98.59%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 80.87% 97.33%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.55% 93.03%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 80.55% 97.23%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146684844
LOTUS LTS0095427
wikiData Q104203171