Cyafricanin E

Details

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Internal ID 94615fbe-355f-491c-8df3-c6e30b598137
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids
IUPAC Name (1S,2R,5S,10R,12R,13S,14R)-1,14-dihydroxy-13-(hydroxymethyl)-8-(1-hydroxypropan-2-yl)-2,5-dimethyl-15-oxatetracyclo[10.2.1.02,10.05,9]pentadec-8-en-7-one
SMILES (Canonical) CC(CO)C1=C2C3CC4C(C(C(C3(CCC2(CC1=O)C)C)(O4)O)O)CO
SMILES (Isomeric) CC(CO)C1=C2[C@H]3C[C@@H]4[C@H]([C@H]([C@]([C@@]3(CC[C@]2(CC1=O)C)C)(O4)O)O)CO
InChI InChI=1S/C20H30O6/c1-10(8-21)15-13(23)7-18(2)4-5-19(3)12(16(15)18)6-14-11(9-22)17(24)20(19,25)26-14/h10-12,14,17,21-22,24-25H,4-9H2,1-3H3/t10?,11-,12-,14-,17-,18+,19-,20-/m1/s1
InChI Key SVURHEVZWJOPTB-FVLYOGBQSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C20H30O6
Molecular Weight 366.40 g/mol
Exact Mass 366.20423867 g/mol
Topological Polar Surface Area (TPSA) 107.00 Ų
XlogP 0.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Cyafricanin E

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.16% 91.11%
CHEMBL220 P22303 Acetylcholinesterase 94.96% 94.45%
CHEMBL253 P34972 Cannabinoid CB2 receptor 94.38% 97.25%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 92.83% 98.75%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.10% 94.45%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.94% 97.09%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.56% 96.09%
CHEMBL2581 P07339 Cathepsin D 89.93% 98.95%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 88.79% 89.34%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.90% 95.56%
CHEMBL1937 Q92769 Histone deacetylase 2 87.79% 94.75%
CHEMBL218 P21554 Cannabinoid CB1 receptor 87.76% 96.61%
CHEMBL1994 P08235 Mineralocorticoid receptor 86.91% 100.00%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 86.72% 93.04%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 85.49% 96.77%
CHEMBL1914 P06276 Butyrylcholinesterase 84.64% 95.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 84.21% 85.14%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 83.50% 96.90%
CHEMBL340 P08684 Cytochrome P450 3A4 82.59% 91.19%
CHEMBL2996 Q05655 Protein kinase C delta 81.92% 97.79%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.86% 97.14%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.72% 89.00%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 81.20% 92.88%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 80.18% 95.71%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 80.15% 99.23%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146683345
LOTUS LTS0208890
wikiData Q105262466