Curtachalasin O

Details

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Internal ID da7ecc65-018c-41b6-88a3-604cc1fcfc4d
Taxonomy Organoheterocyclic compounds > Isoindoles and derivatives > Isoindolines > Isoindolones
IUPAC Name [(1R,2R,3S,4R,5S,6S,8S,14R,15S)-5-acetyl-15-benzyl-4,5-dihydroxy-6,12,13-trimethyl-11,17-dioxo-16-azatetracyclo[8.7.0.01,14.03,8]heptadeca-9,12-dien-2-yl] acetate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H35NO7/c1-14-11-20-13-21-25(34)16(3)15(2)24-22(12-19-9-7-6-8-10-19)31-28(36)29(21,24)27(38-18(5)33)23(20)26(35)30(14,37)17(4)32/h6-10,13-14,20,22-24,26-27,35,37H,11-12H2,1-5H3,(H,31,36)/t14-,20-,22-,23-,24-,26+,27+,29-,30+/m0/s1
InChI Key NZCTUXDSROTKOV-RSPPTQNKSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C30H35NO7
Molecular Weight 521.60 g/mol
Exact Mass 521.24135246 g/mol
Topological Polar Surface Area (TPSA) 130.00 Ų
XlogP 1.90

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Curtachalasin O

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.78% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.57% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.77% 95.56%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.24% 91.11%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 94.44% 85.14%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.03% 94.45%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 89.92% 95.50%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.74% 97.09%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 87.20% 94.00%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 85.66% 97.64%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 84.82% 93.00%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 84.42% 96.95%
CHEMBL340 P08684 Cytochrome P450 3A4 83.91% 91.19%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 83.55% 94.62%
CHEMBL221 P23219 Cyclooxygenase-1 81.99% 90.17%
CHEMBL4208 P20618 Proteasome component C5 81.72% 90.00%
CHEMBL2535 P11166 Glucose transporter 80.08% 98.75%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146682279
LOTUS LTS0167263
wikiData Q105187829