cudraflavanone A

Details

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Internal ID ceb7fe33-97fd-4351-b65d-ffb86adfd160
Taxonomy Phenylpropanoids and polyketides > Flavonoids > Flavans > 6-prenylated flavans > 6-prenylated flavanones
IUPAC Name (2S)-5,7-dihydroxy-2-(7-hydroxy-2,2-dimethylchromen-6-yl)-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
SMILES (Canonical) CC(=CCC1=C(C2=C(C=C1O)OC(CC2=O)C3=C(C=C4C(=C3)C=CC(O4)(C)C)O)O)C
SMILES (Isomeric) CC(=CCC1=C(C2=C(C=C1O)O[C@@H](CC2=O)C3=C(C=C4C(=C3)C=CC(O4)(C)C)O)O)C
InChI InChI=1S/C25H26O6/c1-13(2)5-6-15-17(26)11-22-23(24(15)29)19(28)12-21(30-22)16-9-14-7-8-25(3,4)31-20(14)10-18(16)27/h5,7-11,21,26-27,29H,6,12H2,1-4H3/t21-/m0/s1
InChI Key XPMCEWWRVJLSLM-NRFANRHFSA-N
Popularity 8 references in papers

Physical and Chemical Properties

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Molecular Formula C25H26O6
Molecular Weight 422.50 g/mol
Exact Mass 422.17293854 g/mol
Topological Polar Surface Area (TPSA) 96.20 Ų
XlogP 5.20

Synonyms

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(2S)-5,7-dihydroxy-2-(7-hydroxy-2,2-dimethylchromen-6-yl)-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
RefChem:128737
5,7-dihydroxy-2-(7-hydroxy-2,2-dimethylchromen-6-yl)-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
87402-92-4
CHEMBL220746
BDBM50193719
(S)-5,7,7''-trihydroxy-2'',2''-dimethyl-6-(3-methylbut-2-enyl)-2,6''-bichroman-4-one
(S)-5,7-dihydroxy-2-(7-hydroxy-2,2-dimethyl-2H-chromen-6-yl)-6-(3-methylbut-2-enyl)chroman-4-one

2D Structure

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2D Structure of cudraflavanone A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.57% 91.11%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.34% 85.14%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.98% 94.45%
CHEMBL2581 P07339 Cathepsin D 96.50% 98.95%
CHEMBL1806 P11388 DNA topoisomerase II alpha 94.03% 89.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.56% 96.09%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 87.91% 93.40%
CHEMBL1293249 Q13887 Kruppel-like factor 5 87.39% 86.33%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 86.42% 91.07%
CHEMBL1994 P08235 Mineralocorticoid receptor 86.37% 100.00%
CHEMBL4208 P20618 Proteasome component C5 85.87% 90.00%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 85.64% 89.34%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.10% 99.23%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.50% 95.89%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 83.61% 90.71%
CHEMBL3401 O75469 Pregnane X receptor 83.33% 94.73%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 83.33% 95.56%
CHEMBL3004 P33527 Multidrug resistance-associated protein 1 82.96% 96.37%
CHEMBL2964 P36507 Dual specificity mitogen-activated protein kinase kinase 2 82.73% 80.00%
CHEMBL1951 P21397 Monoamine oxidase A 81.96% 91.49%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 81.19% 92.68%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Euchresta japonica
Maclura pomifera
Maclura tricuspidata

Cross-Links

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PubChem 21721847
NPASS NPC267375
ChEMBL CHEMBL220746
LOTUS LTS0144445
wikiData Q104399338