Cruentaren A

Details

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Internal ID f21af063-809d-48af-8557-8aab1c3cd983
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name N-[(Z)-7-[(6Z)-10,16-dihydroxy-14-methoxy-9-methyl-2-oxo-3-oxabicyclo[10.4.0]hexadeca-1(12),6,13,15-tetraen-4-yl]-6-hydroxy-5-methyloct-2-enyl]-3-hydroxy-2-methylhexanamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C33H51NO8/c1-7-12-26(35)22(4)32(39)34-16-11-10-14-21(3)31(38)23(5)29-15-9-8-13-20(2)27(36)18-24-17-25(41-6)19-28(37)30(24)33(40)42-29/h8-11,17,19-23,26-27,29,31,35-38H,7,12-16,18H2,1-6H3,(H,34,39)/b9-8-,11-10-
InChI Key UXPPKIOUXFFKDI-XESWYYRISA-N
Popularity 13 references in papers

Physical and Chemical Properties

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Molecular Formula C33H51NO8
Molecular Weight 589.80 g/mol
Exact Mass 589.36146759 g/mol
Topological Polar Surface Area (TPSA) 146.00 Ų
XlogP 5.80

Synonyms

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N-[(Z)-7-[(6Z)-10,16-Dihydroxy-14-methoxy-9-methyl-2-oxo-3-oxabicyclo[10.4.0]hexadeca-1(12),6,13,15-tetraen-4-yl]-6-hydroxy-5-methyloct-2-enyl]-3-hydroxy-2-methylhexanamide
N-((Z)-7-((6Z)-10,16-dihydroxy-14-methoxy-9-methyl-2-oxo-3-oxabicyclo(10.4.0)hexadeca-1(12),6,13,15-tetraen-4-yl)-6-hydroxy-5-methyloct-2-enyl)-3-hydroxy-2-methylhexanamide
RefChem:128573
SCHEMBL29366571
CHEBI:188805

2D Structure

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2D Structure of Cruentaren A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.05% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.49% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.68% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.33% 94.45%
CHEMBL3060 Q9Y345 Glycine transporter 2 94.71% 99.17%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.31% 95.56%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 93.97% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 92.88% 89.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.14% 85.14%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 91.10% 91.07%
CHEMBL2964 P36507 Dual specificity mitogen-activated protein kinase kinase 2 91.01% 80.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 90.99% 97.14%
CHEMBL340 P08684 Cytochrome P450 3A4 90.76% 91.19%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 90.65% 90.71%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.61% 99.23%
CHEMBL2535 P11166 Glucose transporter 88.97% 98.75%
CHEMBL3401 O75469 Pregnane X receptor 88.33% 94.73%
CHEMBL226 P30542 Adenosine A1 receptor 85.78% 95.93%
CHEMBL2179 P04062 Beta-glucocerebrosidase 84.60% 85.31%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.75% 97.09%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 83.52% 96.25%
CHEMBL261 P00915 Carbonic anhydrase I 82.92% 96.76%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 82.66% 95.50%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 82.10% 96.38%
CHEMBL3359 P21462 Formyl peptide receptor 1 81.99% 93.56%
CHEMBL4208 P20618 Proteasome component C5 81.57% 90.00%
CHEMBL255 P29275 Adenosine A2b receptor 80.77% 98.59%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 16091466
LOTUS LTS0107233
wikiData Q77568370