Coryximine

Details

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Internal ID 46335292-fa28-4961-bc24-94b6d917c7dd
Taxonomy Organoheterocyclic compounds > Tetrahydroisoquinolines
IUPAC Name 5-[[(5R)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]methyl]-1,3-benzodioxole-4-carboxylic acid
SMILES (Canonical) CN1CCC2=CC3=C(C=C2C1CC4=C(C5=C(C=C4)OCO5)C(=O)O)OCO3
SMILES (Isomeric) CN1CCC2=CC3=C(C=C2[C@H]1CC4=C(C5=C(C=C4)OCO5)C(=O)O)OCO3
InChI InChI=1S/C20H19NO6/c1-21-5-4-11-7-16-17(26-9-25-16)8-13(11)14(21)6-12-2-3-15-19(27-10-24-15)18(12)20(22)23/h2-3,7-8,14H,4-6,9-10H2,1H3,(H,22,23)/t14-/m1/s1
InChI Key MVXPONFJJHYSIL-CQSZACIVSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C20H19NO6
Molecular Weight 369.40 g/mol
Exact Mass 369.12123733 g/mol
Topological Polar Surface Area (TPSA) 77.50 Ų
XlogP 0.70

Synonyms

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AKOS040763258
127460-61-1

2D Structure

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2D Structure of Coryximine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.07% 96.09%
CHEMBL2581 P07339 Cathepsin D 96.23% 98.95%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 95.85% 96.77%
CHEMBL4040 P28482 MAP kinase ERK2 95.46% 83.82%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.52% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.47% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.34% 95.56%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 89.38% 95.89%
CHEMBL1293249 Q13887 Kruppel-like factor 5 85.00% 86.33%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 82.81% 92.62%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 81.50% 90.24%
CHEMBL4208 P20618 Proteasome component C5 80.99% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 21582945
LOTUS LTS0213515
wikiData Q105173428