Cortistatin K
| Internal ID | 6a40641b-efe5-412d-a2cf-e1691a1e225d |
| Taxonomy | Organoheterocyclic compounds > Isoquinolines and derivatives |
| IUPAC Name | (1S,2R,5S,6R,14R,16R)-5-isoquinolin-7-yl-N,N,6-trimethyl-19-oxapentacyclo[14.2.1.01,9.02,6.011,16]nonadeca-9,11-dien-14-amine |
| SMILES (Canonical) | |
| SMILES (Isomeric) | |
| InChI | InChI=1S/C30H36N2O/c1-28-12-10-24-17-23-6-7-25(32(2)3)18-29(23)13-14-30(24,33-29)27(28)9-8-26(28)21-5-4-20-11-15-31-19-22(20)16-21/h4-6,11,15-17,19,25-27H,7-10,12-14,18H2,1-3H3/t25-,26-,27-,28-,29-,30-/m1/s1 |
| InChI Key | BGHODGXGMJFOQR-VHNXJUCRSA-N |
| Popularity | 3 references in papers |
| Molecular Formula | C30H36N2O |
| Molecular Weight | 440.60 g/mol |
| Exact Mass | 440.282763776 g/mol |
| Topological Polar Surface Area (TPSA) | 25.40 Ų |
| XlogP | 5.00 |
| CHEMBL240757 |
| SCHEMBL12431860 |
| DTXSID601336422 |
| 944804-64-2 |
| Target | Value | Probability (raw) | Probability (%) |
|---|---|---|---|
| No predicted properties yet! | |||
Proven Targets:
| CHEMBL ID | UniProt ID | Name | Min activity | Assay type | Source |
|---|---|---|---|---|---|
| No proven targets yet! | |||||
Predicted Targets (via Super-PRED):
| CHEMBL ID | UniProt ID | Name | Probability | Model accuracy |
|---|---|---|---|---|
| CHEMBL3524 | P56524 | Histone deacetylase 4 | 95.76% | 92.97% |
| CHEMBL226 | P30542 | Adenosine A1 receptor | 94.92% | 95.93% |
| CHEMBL3251 | P19838 | Nuclear factor NF-kappa-B p105 subunit | 94.26% | 96.09% |
| CHEMBL6175 | Q9H3R0 | Lysine-specific demethylase 4C | 93.39% | 96.69% |
| CHEMBL4145 | Q9UKV0 | Histone deacetylase 9 | 92.57% | 85.49% |
| CHEMBL3137262 | O60341 | LSD1/CoREST complex | 91.96% | 97.09% |
| CHEMBL5608 | Q16288 | NT-3 growth factor receptor | 89.70% | 95.89% |
| CHEMBL5697 | Q9GZT9 | Egl nine homolog 1 | 89.54% | 93.40% |
| CHEMBL241 | Q14432 | Phosphodiesterase 3A | 89.33% | 92.94% |
| CHEMBL2000 | P03952 | Plasma kallikrein | 88.59% | 93.92% |
| CHEMBL344 | Q99705 | Melanin-concentrating hormone receptor 1 | 88.27% | 92.50% |
| CHEMBL5619 | P27695 | DNA-(apurinic or apyrimidinic site) lyase | 88.18% | 91.11% |
| CHEMBL2553 | Q15418 | Ribosomal protein S6 kinase alpha 1 | 87.70% | 85.11% |
| CHEMBL5896 | O75164 | Lysine-specific demethylase 4A | 86.47% | 99.09% |
| CHEMBL2635 | P51452 | Dual specificity protein phosphatase 3 | 86.45% | 94.00% |
| CHEMBL1907601 | P11802 | Cyclin-dependent kinase 4/cyclin D1 | 86.06% | 98.99% |
| CHEMBL4224 | P49759 | Dual specificty protein kinase CLK1 | 85.53% | 85.30% |
| CHEMBL284 | P27487 | Dipeptidyl peptidase IV | 85.05% | 95.69% |
| CHEMBL2039 | P27338 | Monoamine oxidase B | 84.99% | 92.51% |
| CHEMBL2335 | P42785 | Lysosomal Pro-X carboxypeptidase | 84.90% | 100.00% |
| CHEMBL2581 | P07339 | Cathepsin D | 84.46% | 98.95% |
| CHEMBL2716 | Q8WUI4 | Histone deacetylase 7 | 83.53% | 89.44% |
| CHEMBL3713062 | P10646 | Tissue factor pathway inhibitor | 83.04% | 97.33% |
| CHEMBL1994 | P08235 | Mineralocorticoid receptor | 81.75% | 100.00% |
| CHEMBL5845 | P23415 | Glycine receptor subunit alpha-1 | 81.68% | 90.71% |
| CHEMBL5339 | Q5NUL3 | G-protein coupled receptor 120 | 81.50% | 95.78% |
| CHEMBL4105838 | Q96GG9 | DCN1-like protein 1 | 81.36% | 95.00% |
| CHEMBL2378 | P30307 | Dual specificity phosphatase Cdc25C | 81.07% | 96.67% |
| CHEMBL2243 | O00519 | Anandamide amidohydrolase | 81.01% | 97.53% |
| CHEMBL1951 | P21397 | Monoamine oxidase A | 80.89% | 91.49% |
| CHEMBL255 | P29275 | Adenosine A2b receptor | 80.65% | 98.59% |
| CHEMBL1293249 | Q13887 | Kruppel-like factor 5 | 80.52% | 86.33% |
| CHEMBL3192 | Q9BY41 | Histone deacetylase 8 | 80.15% | 93.99% |
Below are displayed all the plants proven (via scientific papers) to contain this
compound!
To see more specific details click the taxa you are interested in.
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| There are no matching plants. |
| PubChem | 16736905 |
| LOTUS | LTS0188367 |
| wikiData | Q104935560 |