Cortistatin G
| Internal ID | 5b4964b8-e33b-4de4-867d-37353eb9ac75 |
| Taxonomy | Organoheterocyclic compounds > Pyridines and derivatives > Methylpyridines |
| IUPAC Name | (1S,2R,5R,6R,14R,16R)-N,N,6-trimethyl-5-[(E,2R)-4-(3-methyl-4-pyridinyl)but-3-en-2-yl]-19-oxapentacyclo[14.2.1.01,9.02,6.011,16]nonadeca-9,11-dien-14-amine |
| SMILES (Canonical) | |
| SMILES (Isomeric) | |
| InChI | InChI=1S/C31H42N2O/c1-21(6-7-23-13-17-32-20-22(23)2)27-10-11-28-29(27,3)14-12-25-18-24-8-9-26(33(4)5)19-30(24)15-16-31(25,28)34-30/h6-8,13,17-18,20-21,26-28H,9-12,14-16,19H2,1-5H3/b7-6+/t21-,26-,27-,28-,29-,30-,31-/m1/s1 |
| InChI Key | DWEARRASECQSHP-YTQBCWRKSA-N |
| Popularity | 1 reference in papers |
| Molecular Formula | C31H42N2O |
| Molecular Weight | 458.70 g/mol |
| Exact Mass | 458.329713967 g/mol |
| Topological Polar Surface Area (TPSA) | 25.40 Ų |
| XlogP | 5.50 |
| Cortistatine G |
| Cortistatine G, (-)- |
| UNII-KEP0299WIL |
| KEP0299WIL |
| 941271-09-6 |
| 10a,12a-Epoxybenzo(4,5)cyclohept(1,2-E)inden-9-amine, 1,2,3,3a,4,5,8,9,10,11,12,12b-dodecahydro-N,N,3a-trimethyl-3-((1R,3E)-1-methyl-3-(3-methyl-4-pyridinyl)prop-3-en-1-yl)-, (3R,3aR,9R,10aR,12aS,12bR)- |
| DTXSID901336419 |
| Q27282220 |
| Target | Value | Probability (raw) | Probability (%) |
|---|---|---|---|
| No predicted properties yet! | |||
Proven Targets:
| CHEMBL ID | UniProt ID | Name | Min activity | Assay type | Source |
|---|---|---|---|---|---|
| No proven targets yet! | |||||
Predicted Targets (via Super-PRED):
| CHEMBL ID | UniProt ID | Name | Probability | Model accuracy |
|---|---|---|---|---|
| CHEMBL226 | P30542 | Adenosine A1 receptor | 93.02% | 95.93% |
| CHEMBL2581 | P07339 | Cathepsin D | 92.86% | 98.95% |
| CHEMBL3524 | P56524 | Histone deacetylase 4 | 92.70% | 92.97% |
| CHEMBL6175 | Q9H3R0 | Lysine-specific demethylase 4C | 92.37% | 96.69% |
| CHEMBL202 | P00374 | Dihydrofolate reductase | 91.84% | 89.92% |
| CHEMBL3251 | P19838 | Nuclear factor NF-kappa-B p105 subunit | 91.07% | 96.09% |
| CHEMBL5608 | Q16288 | NT-3 growth factor receptor | 90.72% | 95.89% |
| CHEMBL5619 | P27695 | DNA-(apurinic or apyrimidinic site) lyase | 90.38% | 91.11% |
| CHEMBL5896 | O75164 | Lysine-specific demethylase 4A | 89.68% | 99.09% |
| CHEMBL5103 | Q969S8 | Histone deacetylase 10 | 89.33% | 90.08% |
| CHEMBL2179 | P04062 | Beta-glucocerebrosidase | 87.67% | 85.31% |
| CHEMBL5697 | Q9GZT9 | Egl nine homolog 1 | 87.67% | 93.40% |
| CHEMBL2093869 | P05106 | Integrin alpha-IIb/beta-3 | 87.12% | 95.42% |
| CHEMBL253 | P34972 | Cannabinoid CB2 receptor | 86.73% | 97.25% |
| CHEMBL5805 | Q9NR97 | Toll-like receptor 8 | 85.64% | 96.25% |
| CHEMBL2335 | P42785 | Lysosomal Pro-X carboxypeptidase | 85.50% | 100.00% |
| CHEMBL2000 | P03952 | Plasma kallikrein | 85.11% | 93.92% |
| CHEMBL4005 | P42336 | PI3-kinase p110-alpha subunit | 84.66% | 97.47% |
| CHEMBL3492 | P49721 | Proteasome Macropain subunit | 83.98% | 90.24% |
| CHEMBL2337 | P48067 | Glycine transporter 1 | 83.92% | 95.45% |
| CHEMBL3192 | Q9BY41 | Histone deacetylase 8 | 83.86% | 93.99% |
| CHEMBL284 | P27487 | Dipeptidyl peptidase IV | 83.04% | 95.69% |
| CHEMBL1806 | P11388 | DNA topoisomerase II alpha | 82.86% | 89.00% |
| CHEMBL1075094 | Q16236 | Nuclear factor erythroid 2-related factor 2 | 82.26% | 96.00% |
| CHEMBL1966 | Q02127 | Dihydroorotate dehydrogenase | 82.23% | 96.09% |
| CHEMBL1994 | P08235 | Mineralocorticoid receptor | 81.94% | 100.00% |
| CHEMBL3310 | Q96DB2 | Histone deacetylase 11 | 81.69% | 88.56% |
| CHEMBL3746 | P80365 | 11-beta-hydroxysteroid dehydrogenase 2 | 81.62% | 94.78% |
| CHEMBL3202 | P48147 | Prolyl endopeptidase | 81.51% | 90.65% |
| CHEMBL3137262 | O60341 | LSD1/CoREST complex | 81.19% | 97.09% |
| CHEMBL5845 | P23415 | Glycine receptor subunit alpha-1 | 80.88% | 90.71% |
| CHEMBL3713062 | P10646 | Tissue factor pathway inhibitor | 80.88% | 97.33% |
| CHEMBL3359 | P21462 | Formyl peptide receptor 1 | 80.26% | 93.56% |
| CHEMBL290 | Q13370 | Phosphodiesterase 3B | 80.26% | 94.00% |
| CHEMBL3880 | P07900 | Heat shock protein HSP 90-alpha | 80.18% | 96.21% |
| CHEMBL4203 | Q9HAZ1 | Dual specificity protein kinase CLK4 | 80.14% | 94.45% |
| CHEMBL255 | P29275 | Adenosine A2b receptor | 80.09% | 98.59% |
Below are displayed all the plants proven (via scientific papers) to contain this
compound!
To see more specific details click the taxa you are interested in.
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| There are no matching plants. |
| PubChem | 72710752 |
| LOTUS | LTS0102724 |
| wikiData | Q27282220 |