Coniosetin

Details

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Internal ID 78cf94da-b710-455e-bd83-21e053b6a904
Taxonomy Organoheterocyclic compounds > Pyrrolidines > Pyrrolidones > Pyrrolidine-3-ones
IUPAC Name (3E)-3-[[(1S,2R,4aS,6R,8aR)-1,3,6-trimethyl-2-[(1E,3E)-penta-1,3-dienyl]-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]-hydroxymethylidene]-5-(1-hydroxyethyl)pyrrolidine-2,4-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C25H35NO4/c1-6-7-8-9-18-15(3)13-17-12-14(2)10-11-19(17)25(18,5)23(29)20-22(28)21(16(4)27)26-24(20)30/h6-9,13-14,16-19,21,27,29H,10-12H2,1-5H3,(H,26,30)/b7-6+,9-8+,23-20+/t14-,16?,17+,18-,19-,21?,25-/m1/s1
InChI Key ISHIUSZGAFLPLK-MSLMHWDWSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C25H35NO4
Molecular Weight 413.50 g/mol
Exact Mass 413.25660860 g/mol
Topological Polar Surface Area (TPSA) 86.60 Ų
XlogP 4.90

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Coniosetin

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 96.63% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.21% 95.56%
CHEMBL253 P34972 Cannabinoid CB2 receptor 94.56% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.89% 96.09%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 93.15% 85.30%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.23% 85.14%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.02% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.36% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.29% 97.09%
CHEMBL221 P23219 Cyclooxygenase-1 89.88% 90.17%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 87.27% 92.88%
CHEMBL3359 P21462 Formyl peptide receptor 1 85.35% 93.56%
CHEMBL1937 Q92769 Histone deacetylase 2 84.85% 94.75%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 83.75% 85.11%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.74% 89.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.64% 100.00%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 83.55% 96.47%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 82.59% 93.04%
CHEMBL1907 P15144 Aminopeptidase N 81.26% 93.31%
CHEMBL4072 P07858 Cathepsin B 81.19% 93.67%
CHEMBL1293249 Q13887 Kruppel-like factor 5 80.97% 86.33%
CHEMBL3492 P49721 Proteasome Macropain subunit 80.87% 90.24%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 80.27% 93.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 54724406
LOTUS LTS0082424
wikiData Q75064180