Communesin I

Details

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Internal ID 6706ce13-f22b-4d7e-88f8-8ff517dd8e3d
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Pyridoindoles > Alpha carbolines
IUPAC Name (3S)-1-[(2S,6R,14R,22R,25S)-25-[(2R)-3,3-dimethyloxiran-2-yl]-15-methyl-1,3,13,15-tetrazaheptacyclo[18.4.1.02,6.06,22.07,12.014,22.016,21]pentacosa-7,9,11,16,18,20-hexaen-3-yl]-3-hydroxyhexan-1-one
SMILES (Canonical) CCCC(CC(=O)N1CCC23C1N4CCC25C(NC6=CC=CC=C36)N(C7=CC=CC(=C57)C4C8C(O8)(C)C)C)O
SMILES (Isomeric) CCC[C@@H](CC(=O)N1CC[C@]23[C@H]1N4CC[C@]25[C@H](NC6=CC=CC=C36)N(C7=CC=CC(=C57)[C@H]4[C@@H]8C(O8)(C)C)C)O
InChI InChI=1S/C32H40N4O3/c1-5-9-19(37)18-24(38)35-16-14-31-21-11-6-7-12-22(21)33-28-32(31)15-17-36(29(31)35)26(27-30(2,3)39-27)20-10-8-13-23(25(20)32)34(28)4/h6-8,10-13,19,26-29,33,37H,5,9,14-18H2,1-4H3/t19-,26-,27+,28+,29+,31-,32-/m0/s1
InChI Key MDCQGUSSMLOSLN-RQIFQPJOSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C32H40N4O3
Molecular Weight 528.70 g/mol
Exact Mass 528.31004115 g/mol
Topological Polar Surface Area (TPSA) 71.60 Ų
XlogP 4.00

Synonyms

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SCHEMBL19609073

2D Structure

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2D Structure of Communesin I

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.69% 96.09%
CHEMBL2581 P07339 Cathepsin D 99.04% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.87% 85.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.93% 86.33%
CHEMBL3359 P21462 Formyl peptide receptor 1 91.87% 93.56%
CHEMBL5028 O14672 ADAM10 88.69% 97.50%
CHEMBL233 P35372 Mu opioid receptor 88.53% 97.93%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 87.96% 94.62%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 86.43% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 86.39% 95.56%
CHEMBL4227 P25090 Lipoxin A4 receptor 85.28% 100.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.18% 99.23%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 84.17% 97.50%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.85% 94.45%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.01% 97.09%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 82.99% 82.69%
CHEMBL3310 Q96DB2 Histone deacetylase 11 81.64% 88.56%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 81.11% 94.08%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 81.11% 90.24%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 80.36% 98.33%
CHEMBL2096618 P11274 Bcr/Abl fusion protein 80.33% 85.83%
CHEMBL2094135 Q96BI3 Gamma-secretase 80.21% 98.05%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 132137808
LOTUS LTS0085884
wikiData Q75064036