Hexanoic acid, 3,7-dimethyl-6-octen-1-yl ester

Details

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Internal ID 06768bf2-4935-421f-b41d-7b777a9595ac
Taxonomy Lipids and lipid-like molecules > Fatty Acyls > Fatty alcohol esters
IUPAC Name 3,7-dimethyloct-6-enyl hexanoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C16H30O2/c1-5-6-7-11-16(17)18-13-12-15(4)10-8-9-14(2)3/h9,15H,5-8,10-13H2,1-4H3
InChI Key KNYRCCKTQMBSFP-UHFFFAOYSA-N
Popularity 12 references in papers

Physical and Chemical Properties

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Molecular Formula C16H30O2
Molecular Weight 254.41 g/mol
Exact Mass 254.224580195 g/mol
Topological Polar Surface Area (TPSA) 26.30 Ų
XlogP 5.70
Atomic LogP (AlogP) 4.88
H-Bond Acceptor 2
H-Bond Donor 0
Rotatable Bonds 10

Synonyms

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Citronellyl caproate
10580-25-3
3,7-dimethyloct-6-enyl hexanoate
Hexanoic acid, 3,7-dimethyl-6-octenyl ester
3,7-dimethyloct-6-en-1-yl hexanoate
Hexanoic acid, 3,7-dimethyl-6-octen-1-yl ester
EINECS 234-175-1
CITRONELLYLCAPROATE
SCHEMBL560301
DTXSID10864291
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Hexanoic acid, 3,7-dimethyl-6-octen-1-yl ester

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
Human Intestinal Absorption + 0.9968 99.68%
Caco-2 + 0.9519 95.19%
Blood Brain Barrier + 0.9000 90.00%
Human oral bioavailability - 0.6286 62.86%
Subcellular localzation Mitochondria 0.5488 54.88%
OATP2B1 inhibitior - 0.8491 84.91%
OATP1B1 inhibitior + 0.9010 90.10%
OATP1B3 inhibitior + 0.9094 90.94%
MATE1 inhibitior - 0.9000 90.00%
OCT2 inhibitior - 0.7750 77.50%
BSEP inhibitior + 0.6452 64.52%
P-glycoprotein inhibitior - 0.8914 89.14%
P-glycoprotein substrate - 0.8214 82.14%
CYP3A4 substrate - 0.5000 50.00%
CYP2C9 substrate + 0.5955 59.55%
CYP2D6 substrate - 0.8761 87.61%
CYP3A4 inhibition - 0.9267 92.67%
CYP2C9 inhibition - 0.9105 91.05%
CYP2C19 inhibition - 0.8736 87.36%
CYP2D6 inhibition - 0.9284 92.84%
CYP1A2 inhibition - 0.6823 68.23%
CYP2C8 inhibition - 0.9398 93.98%
CYP inhibitory promiscuity - 0.6530 65.30%
UGT catelyzed - 0.0000 0.00%
Carcinogenicity (binary) - 0.6200 62.00%
Carcinogenicity (trinary) Non-required 0.5336 53.36%
Eye corrosion + 0.7056 70.56%
Eye irritation + 0.8466 84.66%
Skin irritation + 0.5000 50.00%
Skin corrosion - 0.9912 99.12%
Ames mutagenesis - 0.9400 94.00%
Human Ether-a-go-go-Related Gene inhibition - 0.4646 46.46%
Micronuclear - 1.0000 100.00%
Hepatotoxicity - 0.6750 67.50%
skin sensitisation - 0.6074 60.74%
Respiratory toxicity - 0.8556 85.56%
Reproductive toxicity - 1.0000 100.00%
Mitochondrial toxicity - 0.9875 98.75%
Nephrotoxicity + 0.5212 52.12%
Acute Oral Toxicity (c) IV 0.4928 49.28%
Estrogen receptor binding - 0.9027 90.27%
Androgen receptor binding - 0.8485 84.85%
Thyroid receptor binding + 0.5889 58.89%
Glucocorticoid receptor binding - 0.6350 63.50%
Aromatase binding - 0.8533 85.33%
PPAR gamma - 0.6612 66.12%
Honey bee toxicity - 0.9510 95.10%
Biodegradation + 0.7000 70.00%
Crustacea aquatic toxicity - 0.5506 55.06%
Fish aquatic toxicity + 0.9876 98.76%

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3060 Q9Y345 Glycine transporter 2 96.96% 99.17%
CHEMBL2581 P07339 Cathepsin D 96.00% 98.95%
CHEMBL2265 P23141 Acyl coenzyme A:cholesterol acyltransferase 95.74% 85.94%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 95.36% 92.08%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.98% 96.09%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 94.86% 97.29%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.85% 94.45%
CHEMBL221 P23219 Cyclooxygenase-1 91.54% 90.17%
CHEMBL299 P17252 Protein kinase C alpha 90.70% 98.03%
CHEMBL3359 P21462 Formyl peptide receptor 1 89.96% 93.56%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.06% 97.25%
CHEMBL202 P00374 Dihydrofolate reductase 87.76% 89.92%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 86.61% 96.47%
CHEMBL2885 P07451 Carbonic anhydrase III 86.51% 87.45%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 85.80% 89.34%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 85.47% 91.24%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 85.40% 91.81%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 85.31% 92.86%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.14% 90.71%
CHEMBL340 P08684 Cytochrome P450 3A4 84.61% 91.19%
CHEMBL3401 O75469 Pregnane X receptor 83.70% 94.73%
CHEMBL1293316 Q9HBX9 Relaxin receptor 1 83.54% 82.50%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 82.77% 96.00%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.47% 100.00%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 82.23% 100.00%
CHEMBL1907 P15144 Aminopeptidase N 81.94% 93.31%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 81.88% 96.00%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 81.33% 94.33%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 80.58% 91.11%
CHEMBL5255 O00206 Toll-like receptor 4 80.53% 92.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

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PubChem 114416
LOTUS LTS0194598
wikiData Q67879811