Citrinadin B

Details

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Internal ID 640bdc87-f1d4-4704-b8ef-4c7c0df116a7
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Amino acids and derivatives > Delta amino acids and derivatives
IUPAC Name (3S,3'aS,6'R,9'aS,10'aR)-7-[(2S)-3,3-dimethyloxirane-2-carbonyl]-10'a-hydroxy-1',1',6'-trimethyl-3'a-(methylamino)spiro[1H-indole-3,2'-3,4,6,7,8,9,9a,10-octahydrocyclopenta[b]quinolizine]-2-one
SMILES (Canonical) CC1CCCC2N1CC3(CC4(C5=CC=CC(=C5NC4=O)C(=O)C6C(O6)(C)C)C(C3(C2)O)(C)C)NC
SMILES (Isomeric) C[C@@H]1CCC[C@@H]2N1C[C@]3(C[C@]4(C5=CC=CC(=C5NC4=O)C(=O)[C@@H]6C(O6)(C)C)C([C@@]3(C2)O)(C)C)NC
InChI InChI=1S/C28H39N3O4/c1-16-9-7-10-17-13-28(34)25(4,5)27(14-26(28,29-6)15-31(16)17)19-12-8-11-18(20(19)30-23(27)33)21(32)22-24(2,3)35-22/h8,11-12,16-17,22,29,34H,7,9-10,13-15H2,1-6H3,(H,30,33)/t16-,17+,22-,26+,27-,28-/m1/s1
InChI Key FMXABKNHBZJYPO-AMZVHIOHSA-N
Popularity 10 references in papers

Physical and Chemical Properties

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Molecular Formula C28H39N3O4
Molecular Weight 481.60 g/mol
Exact Mass 481.29405673 g/mol
Topological Polar Surface Area (TPSA) 94.20 Ų
XlogP 2.10

Synonyms

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(3S,3'aS,6'R,9'aS,10'aR)-7-[(2S)-3,3-dimethyloxirane-2-carbonyl]-10'a-hydroxy-1',1',6'-trimethyl-3'a-(methylamino)spiro[1H-indole-3,2'-3,4,6,7,8,9,9a,10-octahydrocyclopenta[b]quinolizine]-2-one

2D Structure

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2D Structure of Citrinadin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 96.72% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.68% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.27% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 94.64% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.49% 95.56%
CHEMBL4040 P28482 MAP kinase ERK2 93.46% 83.82%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 92.38% 96.77%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 91.58% 93.03%
CHEMBL220 P22303 Acetylcholinesterase 90.17% 94.45%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.31% 95.89%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.08% 86.33%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.03% 99.23%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.01% 97.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 87.50% 97.25%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 87.44% 94.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.62% 94.45%
CHEMBL340 P08684 Cytochrome P450 3A4 82.28% 91.19%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 82.24% 96.00%
CHEMBL4208 P20618 Proteasome component C5 81.79% 90.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.50% 90.71%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 81.20% 96.21%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 80.42% 83.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11641538
LOTUS LTS0123619
wikiData Q104998120