Circumdatin G

Details

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Internal ID 70277ceb-8163-488f-8cdb-8923ed043611
Taxonomy Organoheterocyclic compounds > Pyrimidodiazepines
IUPAC Name (7S)-9-hydroxy-7-methyl-6,7-dihydroquinazolino[3,2-a][1,4]benzodiazepine-5,13-dione
SMILES (Canonical) CC1C2=NC3=C(C=CC=C3O)C(=O)N2C4=CC=CC=C4C(=O)N1
SMILES (Isomeric) C[C@H]1C2=NC3=C(C=CC=C3O)C(=O)N2C4=CC=CC=C4C(=O)N1
InChI InChI=1S/C17H13N3O3/c1-9-15-19-14-11(6-4-8-13(14)21)17(23)20(15)12-7-3-2-5-10(12)16(22)18-9/h2-9,21H,1H3,(H,18,22)/t9-/m0/s1
InChI Key VNCYXASDDCJEJE-VIFPVBQESA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C17H13N3O3
Molecular Weight 307.30 g/mol
Exact Mass 307.09569129 g/mol
Topological Polar Surface Area (TPSA) 82.00 Ų
XlogP 1.60

Synonyms

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CHEMBL2375799
(7S)-9-hydroxy-7-methyl-6,7-dihydroquinazolino[3,2-a][1,4]benzodiazepine-5,13-dione

2D Structure

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2D Structure of Circumdatin G

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3038477 P67870 Casein kinase II alpha/beta 97.92% 99.23%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.68% 85.14%
CHEMBL2581 P07339 Cathepsin D 97.61% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.41% 95.56%
CHEMBL1951 P21397 Monoamine oxidase A 94.83% 91.49%
CHEMBL1937 Q92769 Histone deacetylase 2 93.75% 94.75%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 91.73% 96.09%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.11% 94.00%
CHEMBL2535 P11166 Glucose transporter 87.31% 98.75%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.87% 86.33%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 85.98% 99.15%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 85.74% 93.03%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 85.44% 82.69%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 83.94% 93.65%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 83.24% 96.39%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.01% 89.00%
CHEMBL2085 P14174 Macrophage migration inhibitory factor 82.75% 80.78%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 81.26% 96.67%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10804637
LOTUS LTS0206113
wikiData Q77517451