Ciprofloxacin

Details

• Internal ID: d59c2323-cfac-469f-a90e-02627bab0445
• Taxonomy: Organoheterocyclic compounds > Quinolines and derivatives > Quinoline carboxylic acids
• IUPAC Name: 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• SMILES (Canonical): C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O
• SMILES (Isomeric): C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O
• InChI: InChI=1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)
• InChI Key: MYSWGUAQZAJSOK-UHFFFAOYSA-N
• Popularity: 52,570 references in papers

Physical and Chemical Properties

• Molecular Formula: C₁₇H₁₈FN₃O₃
• Molecular Weight: 331.34 g/mol
• Exact Mass: 331.13321961 g/mol
• Topological Polar Surface Area (TPSA): 72.90 Ų
• XlogP: -1.10

Synonyms

• 85721-33-1
• Ciprobay
• Ciprofloxacine
• Cipro
• Ciproxan
• Ciprofloxacina
• Ciprofloxacinum
• Cipro IV
• Ciprocinol
• Ciprofloxacino
• Cipromycin
• Ciproquinol
• Bacquinor
• Bernoflox
• Cifloxin
• Ciprodar
• Otiprio
• Septicide
• BAY q 3939
• Ciproflox
• Ciprogis
• Ciprolin
• Ciprolon
• Ciprowin
• Ciproxina
• Ciproxine
• Citopcin
• Corsacin
• Fimoflox
• Proflaxin
• Quinolid
• Spitacin
• Superocin
• Zumaflox
• Baflox
• Ciplus
• Ciprecu
• Ciriax
• Ipiflox
• Italnik
• Probiox
• Quintor
• Rancif
• Roxytal
• Cilab
• Cixan
• Cycin
• Loxan
• Unex
• Sophixin Ofteno
• 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• Ciprobay Uro
• Alcon Cilox
• Bi-Cipro
• 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
• Cetraxal
• CPFX
• Cyprobay
• Proksi 250
• Proksi 500
• AuriPro
• Cipro XR
• BAYQ3939
• Bay-09867
• 1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid
• CCRIS 5241
• Linhaliq
• HSDB 6987
• UNII-5E8K9I0O4U
• 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• Ciprofloxacine [INN-French]
• Ciprofloxacinum [INN-Latin]
• Ciprofloxacino [INN-Spanish]
• Ciproxin
• NSC-758467
• BRN 3568352
• 5E8K9I0O4U
• 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
• CIPRO IN DEXTROSE 5% IN PLASTIC CONTAINER
• Ciprofloxacin (Cipro)
• BAY O 9867 FREE BASE
• BAY-O-9867 FREE BASE
• CHEMBL8
• CHEBI:100241
• BAY-Q-3939
• Bay o 9867
• CIPRO IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
• 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-
• Ciprinol
• DTXSID8022824
• BAY-O9867
• Velmonit
• Ciprofloxacin [USAN:USP:INN:BAN]
• Ciprofloxacin monohydrochloride
• 3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-
• CIPRODEX COMPONENT CIPROFLOXACIN
• NSC 758467
• Eni
• CIPROFLOXACIN COMPONENT OF CIPRODEX
• Cipro (TN)
• 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline-carboxylic acid
• 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid
• 1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
• Ciprofloxacine (INN-French)
• Ciprofloxacinum (INN-Latin)
• 1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
• Ciprofloxacino (INN-Spanish)
• CIPROFLOXACIN (MART.)
• CIPROFLOXACIN [MART.]
• CIPROFLOXACIN (USP-RS)
• CIPROFLOXACIN [USP-RS]
• Linhaliq (Liposomal Formulation)
• Linhaliq [Liposomal Formulation]
• CIPROFLOXACIN (EP MONOGRAPH)
• CIPROFLOXACIN [EP MONOGRAPH]
• Ciprofloxacin (USAN:USP:INN:BAN)
• CIPROFLOXACIN (USP MONOGRAPH)
• CIPROFLOXACIN [USP MONOGRAPH]
• BAY-o 9867
• SMR000471901
• NSC620634
• SR-05000001863
• NCGC00016959-01
• CAS-93107-08-5
• rubrum
• Ciprine
• ENROFLOXACIN FOR VETERINARY USE IMPURITY B (EP IMPURITY)
• ENROFLOXACIN FOR VETERINARY USE IMPURITY B [EP IMPURITY]
• Ciprofloxacin In Dextrose 5%
• Bay 09867
• Ciprofloxacin,(S)
• MFCD00185755
• Spectrum_000162
• Ciprofloxacin protomer I
• Ciprofloxacin in Dextrose
• Ciprofloxacin protomer II
• Prestwick0_000113
• Prestwick1_000113
• Prestwick2_000113
• Prestwick3_000113
• Spectrum2_001567
• Spectrum3_001872
• Spectrum4_000874
• Spectrum5_001089
• Cipro (*Hydrochloride*)
• CBMicro_048498
• CIPROFLOXACIN [MI]
• Ciloxan (*Hydrochloride*)
• ciprofloxacin by-compound a
• CIPROFLOXACIN [INN]
• CIPROFLOXACIN [JAN]
• SCHEMBL2900
• CIPROFLOXACIN [HSDB]
• CIPROFLOXACIN [USAN]
• Oprea1_008239
• Oprea1_313572
• BSPBio_000126
• BSPBio_003344
• CIPROFLOXACIN [VANDF]
• KBioGR_001567
• KBioSS_000642
• ANHYDROUS CIPROFLOXACIN
• Ciprofloxacin In Dextrose 5% In Plastic Container
• MLS001336035
• MLS006011837
• BIDD:GT0205
• DivK1c_000095
• SPECTRUM1503614
• BAY q3939
• SPBio_001474
• SPBio_002065
• CIPROFLOXACIN [WHO-DD]
• CIPROFLOXACIN [WHO-IP]
• ciprofloxacin desfluoro-compound
• BPBio1_000140
• DTXCID002824
• BDBM21690
• GTPL10902
• HMS500E17
• KBio1_000095
• KBio2_000642
• KBio2_003210
• KBio2_005778
• KBio3_002846
• Ciprofloxacin (JP17/USP/INN)
• J01MA02
• S01AE03
• S02AA15
• S03AA07
• NINDS_000095
• Bay o 9867 (*Hydrochloride*)
• HMS1922E18
• HMS2090O07
• HMS2093I03
• Pharmakon1600-01503614
• CIPROFLOXACIN [ORANGE BOOK]
• BCP28586
• HY-B0356
• RKL10073
• CCG-39345
• CIPROFLOXACIN EXTENDED RELEASE
• Ciprofloxacin, >=98.0% (HPLC)
• NSC758467
• NSC759028
• s2027
• 719 - Quinolone antibiotics in fish
• 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-quinoline-3-carboxylic acid
• 1-cyclopropyl-6-fluoro-4-oxo-7-piperazinylhydroquinoline-3-carboxylic acid
• AKOS000269653
• CIPROFLOXACINUM [WHO-IP LATIN]
• AC-7613
• DB00537
• KS-5006
• NSC-759028
• IDI1_000095
• SMP1_000125
• Ciprofloxacin 100 microg/mL in Methanol
• NCGC00016959-02
• NCGC00016959-03
• NCGC00016959-04
• NCGC00016959-05
• NCGC00016959-07
• NCGC00095058-01
• NCGC00095058-02
• NCGC00178128-01
• SBI-0048462.P003
• C2510
• FT-0601635
• EN300-08481
• C-6350
• C05349
• D00186
• A841426
• Ciprofloxacin, VETRANAL(TM), analytical standard
• Q256602
• Ciprofloxacin, Antibiotic for Culture Media Use Only
• SR-05000001863-1
• SR-05000001863-3
• BRD-K04804440-311-02-3
• Z56933707
• Ciprofloxacin, European Pharmacopoeia (EP) Reference Standard
• Ciprofloxacin, United States Pharmacopeia (USP) Reference Standard
• 1-Cyclopropyl-6-fluoro-1,4-dihydro 4-oxo-7-[1-piperazinyl)-quinoline-3-carboxylic Acid
• 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7- (1-piperazinyl)-3-quinoline-carboxylic acid
• 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline -3-carboxylic acid
• 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylic acid
• 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)quinoline-3-carboxylic acid
• 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1piperazinyl)-3quinolinecarboxylic acid
• 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(piperazin-1-yl)-quinoline-3-carboxylic acid
• 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinoline carboxylic acid
• 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacid
• 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-4-ium-1-yl-quinoline-3-carboxylate;Ciprofloxacin
• 1-cyclopropyl-6-fluoro-7-(piperazin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
• Ciprofloxacin, Pharmaceutical Secondary Standard; Certified Reference Material
• 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

2D Structure

ADMET Properties (via admetSAR 2)

Target	Value	Probability (raw)	Probability (%)
No predicted properties yet!

Targets

Proven Targets:

No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID	UniProt ID	Name	Probability	Model accuracy
CHEMBL228	P31645	Serotonin transporter	97.50%	95.51%
CHEMBL3807	P17706	T-cell protein-tyrosine phosphatase	96.19%	93.00%
CHEMBL217	P14416	Dopamine D2 receptor	93.87%	95.62%
CHEMBL3251	P19838	Nuclear factor NF-kappa-B p105 subunit	93.84%	96.09%
CHEMBL3137262	O60341	LSD1/CoREST complex	93.66%	97.09%
CHEMBL2581	P07339	Cathepsin D	92.82%	98.95%
CHEMBL3351	Q13085	Acetyl-CoA carboxylase 1	92.58%	93.04%
CHEMBL3384	Q16512	Protein kinase N1	92.46%	80.71%
CHEMBL3108638	O15164	Transcription intermediary factor 1-alpha	92.09%	95.56%
CHEMBL4296	Q15858	Sodium channel protein type IX alpha subunit	91.38%	96.11%
CHEMBL1937	Q92769	Histone deacetylase 2	90.68%	94.75%
CHEMBL5697	Q9GZT9	Egl nine homolog 1	89.97%	93.40%
CHEMBL5619	P27695	DNA-(apurinic or apyrimidinic site) lyase	89.53%	91.11%
CHEMBL1907600	Q00535	Cyclin-dependent kinase 5/CDK5 activator 1	89.39%	93.03%
CHEMBL5608	Q16288	NT-3 growth factor receptor	88.26%	95.89%
CHEMBL3038477	P67870	Casein kinase II alpha/beta	85.76%	99.23%
CHEMBL4261	Q16665	Hypoxia-inducible factor 1 alpha	85.62%	85.14%
CHEMBL2781	P19634	Sodium/hydrogen exchanger 1	85.48%	90.24%
CHEMBL5845	P23415	Glycine receptor subunit alpha-1	85.25%	90.71%
CHEMBL1806	P11388	DNA topoisomerase II alpha	84.77%	89.00%
CHEMBL4531	P17931	Galectin-3	84.42%	96.90%
CHEMBL222	P23975	Norepinephrine transporter	84.09%	96.06%
CHEMBL4072	P07858	Cathepsin B	83.99%	93.67%
CHEMBL3864	Q06124	Protein-tyrosine phosphatase 2C	83.14%	94.42%
CHEMBL1899	P46098	Serotonin 3a (5-HT3a) receptor	82.19%	100.00%
CHEMBL241	Q14432	Phosphodiesterase 3A	82.14%	92.94%
CHEMBL2535	P11166	Glucose transporter	82.02%	98.75%
CHEMBL1293249	Q13887	Kruppel-like factor 5	81.84%	86.33%
CHEMBL1966	Q02127	Dihydroorotate dehydrogenase	81.74%	96.09%
CHEMBL3714130	P46095	G-protein coupled receptor 6	81.44%	97.36%
CHEMBL5852	Q96P65	Pyroglutamylated RFamide peptide receptor	80.96%	85.00%
CHEMBL2243	O00519	Anandamide amidohydrolase	80.34%	97.53%

Plants that contains it

There are no matching plants.

Cross-Links

• PubChem: 2764
• LOTUS: LTS0203821
• wikiData: Q256602