IT-143-B

Details

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Internal ID 7c34c591-2d33-4063-9775-a3e412958628
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids
IUPAC Name 2-[(2E,5E,7E,11E,13E)-10-hydroxy-3,7,9,11,13-pentamethylpentadeca-2,5,7,11,13-pentaenyl]-5,6-dimethoxy-3-methyl-1H-pyridin-4-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C28H41NO4/c1-10-18(2)16-21(5)25(30)22(6)17-20(4)13-11-12-19(3)14-15-24-23(7)26(31)27(32-8)28(29-24)33-9/h10-11,13-14,16-17,22,25,30H,12,15H2,1-9H3,(H,29,31)/b13-11+,18-10+,19-14+,20-17+,21-16+
InChI Key QDBZGOIMALIBKV-JXOBDNEFSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C28H41NO4
Molecular Weight 455.60 g/mol
Exact Mass 455.30355879 g/mol
Topological Polar Surface Area (TPSA) 67.80 Ų
XlogP 7.40

Synonyms

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IT-143-B
2-[(2E,5E,7E,11E,13E)-10-Hydroxy-3,7,9,11,13-pentamethylpentadeca-2,5,7,11,13-pentaenyl]-5,6-dimethoxy-3-methyl-1H-pyridin-4-one

2D Structure

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2D Structure of IT-143-B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.82% 85.14%
CHEMBL1937 Q92769 Histone deacetylase 2 96.76% 94.75%
CHEMBL2581 P07339 Cathepsin D 94.89% 98.95%
CHEMBL2535 P11166 Glucose transporter 94.47% 98.75%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.66% 95.56%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.20% 94.45%
CHEMBL3401 O75469 Pregnane X receptor 90.77% 94.73%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.93% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 89.19% 91.11%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.74% 99.23%
CHEMBL3060 Q9Y345 Glycine transporter 2 88.09% 99.17%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 87.72% 91.07%
CHEMBL5103 Q969S8 Histone deacetylase 10 84.56% 90.08%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 83.95% 96.00%
CHEMBL213 P08588 Beta-1 adrenergic receptor 82.87% 95.56%
CHEMBL4302 P08183 P-glycoprotein 1 82.55% 92.98%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 82.15% 97.21%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 81.66% 95.50%
CHEMBL3310 Q96DB2 Histone deacetylase 11 80.33% 88.56%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 80.32% 92.68%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

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PubChem 9825264
LOTUS LTS0109742
wikiData Q105218726